Washington University

Vadim Arkadievich Markel

John Carl Schotland

Paul Scott Carney

A methodology and concomitant system for the reconstruction of an object from measurements of the transmitted intensity of scattered radiation effected by irradiating the object with a source of radiation. The measurements of the transmitted intensity are both spatially sampled and limited. The transmitted intensity is related to either the absorption coefficient or diffusion coefficient, or both, of the object by an integral operator. The image is directly reconstructed by executing a prescribed mathematical algorithm, as determined with reference to the integral operator, on the transmitted intensity of the scattered radiation. In a preferred embodiment, the data is measured using a paraxial arrangement composed on a single source and a small number of on-axis and off-axis detectors with the arrangement being moved over the measurement surface to measure the set of sampled and limited data.

System and method of image reconstruction for optical tomography with limited data

A methodology and concomitant system for three-dimensional near-field microscopy achieves subwavelength resolution of an object without retrieval of the optical phase. The features of this approach are three-fold: (i) the near-field phase problem is circumvented by employing measurements of the power extinguished from probe fields; (ii) the fields on which the power measurements are performed may be monitored far from the object and thus subwavelength resolution is obtained from far zone measurements; and (iii) by developing an analytic approach to the inverse problem in the form of an explicit inversion formula, an image reconstruction algorithm is produced which is strikingly robust in the presence of noise.

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Richmond Heights, MO, United States of America

Vadim Arkadievich Markel