Council of Scientific and Industrial Research

Vaddu Venkata Narayana Reddy

Jhillu Singh Yadav

Mukund Vinayak Deshpande

Raj Kumar

Sunita Ranjan Deshpande

Preeti Madhukar Chaudhary

Masna Mahesh

Penumatcha Venkata Krishnam Raju

Anand Kumar Bachhawat

Chappeta Venkateswara Reddy

Ganesan Kaliannan

Fazal Shirazi

Sanjoy Paul

Khwaja Ishratullah

Nageshwar Nath Sharma

Tella Ramesh Babu

Nelavelli Malleswara Rao

Bommena Vittal Rao

Baidyanath Mohanty

Bhimrao Bodhanrao Gawali

This invention provides novel substituted 1,4-dioxa-8-azaspiro[4,5]decane compounds of the general formula (1), wherein R1 is selected from phenethyl, 4,6-dimethoxypyrimidin-2-yl and (2-chloro-5-thiazolyl)methyl and R2 is selected from the group consisting of hydroxy, 4-bromo-2-chlorophenoxy, morpholin-4-yl, (2-chloro-5-thiazolyl)methyloxy, benzyloxy, phenylsulfanyl, benzotriazol and 5-chloro-2-fluoroanilino. The present invention also relates to a process for the preparation of novel substituted 1,4-dioxa-8-azaspiro[4,5]decanes of general formula (1). The novel substituted 1,4-dioxa-8-azaspiro[4,5]decane of general formula (1) has fungicidal activity.

Substituted 1, 4-dioxa-8-azaspiro[4,5]decanes useful as fungicides and a process for the preparation thereof

The present invention relates to an environmentally benign process for the preparation of (S)-&#x3b1;-cyano-3-phenoxybenzyl-(S)-2-(4-chlorophenyl)isovalerate from its diastereomeric mixture (RS)-&#x3b1;-cyano-3-phenoxybenzyl-(S)-2-(4-chlorophenyl) isovalerate.

Process for preparing (S)- alpha-cyano-3-phenoxybenzyl-(S)-2-(4-chlorophenyl)-isovalerate

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Hydrabad, India

Vaddu Venkata Narayana Reddy