University of Arkansas

Eisai Inc.

Aesgen, Inc.

V Suzanne Klimberg

Steven E Harms

Larry Suva

Sohelia Korourian

Gal Shafirstein

Edward C Shinal

Paul L Hermonat

Yong Liu

Robert G Petit, Ii

Soheila Korourian

Robert G Ii Petit

The present invention provides compositions and processes for preparing the same wherein the compositions are useful for monitoring breast cancer treatment.

Compositions and methods for monitoring breast cancer treatment

The present invention provides a treatment method to excise a cancerous lesion, such as in the breast, with subsequent ablation of the margin. The method provides for location and excision with ablation under open guidance or guided imaging and for diagnosis by cytology. The method may be a minimally, invasive same day method with diagnosis before or immediately after excision. Also provided is a method of treating close or positive margins of an excisional site of a cancerous lesion in a breast by ablating the margin while monitoring the fluorescence of a fluorophor at the site to determine when ablation of the close or positive margin has occurred.

Minimally invasive diagnosis and treatment for breast cancer

Provided are methods of treating cancer, and/or the side effects of cancer therapy, involving the administration of glutamine, optionally in combination with a carbohydrate carrier that enhances the absorption of glutamine.

Treatment of cancer with glutamine

The present invention provides compositions and a method for monitoring breast cancer treatment.

The present invention provides a minimally invasive, comprehensive same-day diagnosis and treatment method to remove tumor and ablate margins in breast cancer patients, comprising disease diagnosis by MRI and touch preparation cytology, followed by tumor removal and ablation of tumor margins.

Minimally invasive treatment for breast cancer

Methods for screening a patient for a cancer wherein the methods comprise detecting an HPV in a biopsy from a patient are disclosed. Also disclosed are compositions and products for screening and for treating cancer in a patient, as well as methods of treating a patient afflicted with a cancer.

Compositions, methods and products comprising human papillomavirus for detecting and treating a cancer

A novel method of hematoma-directed ultrasound guided excisional breast biopsy is disclosed. In one aspect of the inventon, the hematoma is produced by an injection of the patient's own blood into a pre-selected area to target a lesion. Detection of the targeted lesion and hematoma is achieved with MRI. In a second aspect of the invention, the hematoma is produced by stereotactic core needle breast biopsy in a pre-selected area, and the targeted lesion and hematoma are detected using intraoperative ultrasound. The method avoids many of the disadvantages associated with traditional needle localized breast biopsy. The method can also be used to guide the excision of lesions visualized by MRI, ultrasound, mammography, PET scanning, and scintimammography. The method may be used in any organ and, in particular, the breast.

Growing community of inventors

Little Rock, AR, United States of America

V Suzanne Klimberg