Proteinsimple

Aclara Biosciences, Inc.

Uyen Nguyen

Hui Xu

Torleif Ove Bjornson

Mingqi Zhao

Hilary Sue Lackritz

Antonio J Ricco

Petr Vanysek

Zhu Qun

Embodiments described herein generally relate to cartridges suitable for performing electrophoretic separation of analytes. Cartridges described herein are particularly well suited for reuse. Cartridges described herein can include a reservoir disposed between a capillary and a container containing a run buffer. The reservoir can inhibit run buffer from intruding into the capillary, thereby allowing repeated electrophoretic separations to be more consistent, more accurate, and/or more reliable.

Reusable cartridge for capillary electrophoresis

A microfluidic device having integrated components for conducting chemical operations. Depending upon the desired application, the components include electrodes for manipulating charged entities, heaters, electrochemical detectors, sensors for temperature, pH, fluid flow, and other useful components. The device may be fabricated from a plastic substrate such as, for example, a substantially saturated norbornene based polymer. The components are integrated into the device by adhering an electrically conductive film to the substrate. The film may be made of metal or an electrically conducting ink and is applied to the device through metal deposition, printing, or other methods for applying films. Methods for reducing bubble formation during electrokinetic separation and methods for heating material in a microfluidic device are also disclosed.

Microfluidic chip having integrated electrodes

Growing community of inventors

San Jose, CA, United States of America

Uyen Nguyen