Warner-lambert Company

Goedecke Aktiengesellschaft

Godecke Aktiengesellschaft

Uwe Trostmann

Christoph Schachtele

Claus Rudolph

David Christopher Horwell

Johannes Hartenstein

Edward Roberts

Bruce D Roth

Bharat Kalidas Trivedi

Paul C Unangst

Martyn C Pritchard

Bradley Dean Tait

Hubert G Barth

Hartmut Osswald

Ann Holmes

Reginald S Richardson

Karl Mannhardt

Michael D Mullican

Corinne E Augelli-Szafran

Julian Aranda

Gunter Weinheimer

Reinhard Reck

Hans-Jurgen Betche

Dieter Marme

Walter Kolch

Bis-indolyl maleinimide or indolopyrrolo carbazole containing an amino

2-aminocarboxylic acids and their derivatives, processes for their

Novel unnatural dipeptoids useful as agents in the treatment of obesity, hypersecretion of gastric acid in the gut, gastrin-dependent tumors, or as antipsychotics are disclosed. Further, the compounds are antianxiety agents and antiulcer agents. The compounds are agents useful for preventing the response to withdrawal from chronic treatment or use of nicotine, diazepam, alcohol, cocaine, caffeine, and opioids. The compounds are also useful in treating and/or preventing panic attacks. Also disclosed are pharmaceutical compositions and methods of treatment using the dipeptoids as well as processes for preparing them and novel intermediates useful in their preparation. An additional feature of the invention is the use of the subject compounds to prepare diagnostic compositions.

Amino acid analogs as CCK antagonists

Novel substituted polyhydro-.beta.-carboline derivatives useful as agents in the treatment of obesity, hypersecretion of gastric acid in the gut, gastrin-dependent tumors, or as antipsychotic agents are disclosed. Further the compounds are antianxiety agents and antiulcer agents. Further, the compounds are useful for treating and/or preventing panic attacks. They are agents useful for preventing the response to withdrawal from chronic treatment with or use of nicotine, caffeine, diazepam, alcohol, cocaine or opioids. Also disclosed are pharmaceutical compositions and methods of treatment using the compounds as well as processes for preparing them and novel intermediates useful in their preparation. An additional feature of the invention is the use of the subject compounds in diagnostic compositions.

N-substituted cycloalkyl and polycycloalkyl

The present invention covers a novel series of 2-acyloxypropylamine derivatives, processes for preparing them, compositions containing them, and methods for using them. The compounds are active in the inhibition of protein kinase C and thrombocyto aggregation stimulated by diacylglycerols.

2-acyloxypropylamino derivatives, processes for the preparation thereof,

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March-Hugstetten, Germany

Uwe Trostmann