Pari Pharma Gmbh

Pari Gmbh Spezialisten Fur Effektive Inhalation

Pari Gmbh Spezialisten Fuer Effektive Inhalation

Uwe Schuschnig

Martin Luber

Manfred Keller

Johann Zimmermann

Andreas Böhm

Andreas Johannes Boehm

Jens Gramann

Emir Jelovac

Wolfgang Achtzehner

Titus Selzer

Ulf Krüger

Axel Krüner

Erman Lu

Nicolas Buchmann

Andreas Bohm

Axel Kruener

Nicolas Schwenck

Christoph Fritz

Axel KRÜNER

The invention relates to a nebulizer () comprising an aerosol generator (), a nebulizing chamber () and an outlet (), the aerosol generator () being designed to release an aerosol into the nebulizing chamber () and the outlet () being designed to allow the removal of the aerosol from the nebulizing chamber (). To achieve a high output rate, a wetting surface () is provided in the nebulizing chamber ().

Nebulizer and method for producing a nebulizer

A pharmaceutical aerosol is disclosed which is suitable for delivering an active compound to the mucosa of the nose, the osteomeatal complex or a paranasal sinus. The pressure of the aerosol is not constant, but pulsates at a frequency from about 10 to 90 Hz. The aerosol is further characterised in that it exhibits a low effective flow rate of less than about 5 liters per minute. The aerosol is, inter alia, suitable for the prevention, management, or treatment of a disease, symptom, or condition affecting the nose or the paranasal sinuses, such as acute and chronic sinusitis.

Aerosols for sinunasal drug delivery

In a first aspect, the invention relates to a method for operating an aerosol inhalation device (), comprising the steps of transporting a certain amount of an aerosol to a desired location outside said device () and vibrating the transported aerosol when it has reached said desired location. In a second aspect, the invention relates to an aerosol inhalation device () comprising a pump () for flowing a certain amount of an aerosol to a desired location outside the device (), a vibrator () for vibrating the transported aerosol in a vibration mode and a control configured to actuate the vibrator () for vibrating the flowed aerosol only when it has reached said desired location.

Method for operating an aerosol inhalation device and aerosol inhalation device

A pharmaceutical aerosol is disclosed which is suitable for delivering an active compound to the mucosa of the nose, the osteomeatal complex or a paranasal sinus. The pressure of the aerosol is not constant, but pulsates at a frequency from about 10 to 90 Hz. The aerosol is further characterized in that it exhibits a low effective flow rate of less than about 5 liters per minute. The aerosol is, inter alia, suitable for the prevention, management, or treatment of a disease, symptom, or condition affecting the nose or the paranasal sinuses, such as acute and chronic sinusitis.

Aerosol therapy device comprising a nebuliser () for generating an aerosol and forming an aerosol flow, a first nosepiece () for introducing the aerosol flow into one of the two nostrils () of a user, a pressure fluctuation source for generating a pressure fluctuation (DS), a second nosepiece () for introducing the pressure fluctuation into the other of the two nostrils () of the user in order to superimpose the pressure fluctuation and the aerosol flow, and a sensor system comprising a first pressure sensor () for detecting the signal of the pressure fluctuation that arrives at the first nosepiece (), and an evaluation means () that concludes the degree of closure of the velum of the user based on the signal.

Aerosol therapy device

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Munich, Germany

Uwe Schuschnig