Basf Aktiengesellschaft

Uwe Pressler

Wolfgang Ladner

Bernhard Hauer

Horst Ralf Staudenmaier

Joachim Meyer

Ursula Mueller

Friedhelm Balkenhohl

Ursula Schnell

Wolfgang Siegel

Hardo Siegel

Matthias Kroner

Tom Witzel

Detlef Kratz

Christoph Nubling

Rudolf Bazner

The present invention relates to a novel process for the preparation, by fermentation, of compounds of the formula I ##STR1## where R.sup.1 is hydrogen, fluorine, chlorine or bromine.

Fermentative preparation of 2,5-dihydroxyphenylacetic acid with Beauveria

A process for hydroxylating compounds of the formula ##STR1## where n, A and R.sup.1 to R.sup.4 have the meanings stated in the description, with the aid of microorganisms of the genus Beauveria.

Process for the hydroxylation of aromatic acids using strains of the

A process for producing microorganisms which have increased L-lysine productivity is described. The process makes use of microorganisms of the genera Corynebacterium and Brevibacterium which are resistant to feedback inhibition by 2-azido-.epsilon.-caprolactam.

Azido-caprolactam as inhibitor for selecting microorganisms with high

Process for preparing D,L-aspartic acid from ammonium salts of the

Biotechnological perparation of alcohols, aldehydes and carboxylic acids

2-hydroxyphenylacetic acid is prepared from phenylacetic acid by fermentation with suitable microorganisms.

Preparation of 2-hydroxyphenylacetic acid by fermentation

Resolution of the racemates of primary and secondary amines by

A process for preparing enantiomerically pure lactams of the formula I ##STR1## where R.sup.1 and R.sup.2 are each, independently of one another, H, unsubstituted or substituted C.sub.1 -C.sub.4 -alkyl, unsubstituted or substituted C.sub.2 -C.sub.4 -alkenyl, unsubstituted or substituted aryl, (CH.sub.2).sub.n --COOH with n=0, 1, 2, 3, and X is 1, 2, 3, 4, 5, from a racemate of the formula I by. allowing a biocatalyst which selectively converts one enantiomer from I to act on the racemic mixture of I, and isolating the unconverted enantiomer from the resulting mixture of products.

Preparation of enantiomerically pure lactams

The invention relates to a novel process for preparing 3-hydroxyphenylacetic acid by cultivating a fungus of the genus Rhizoctonia, Ceratobasidium and Pellicularia in the presence of a phenyl compound of the formula I ##STR1## where X is COOR, CH.sub.2 OH, CH.sub.2 NH.sub.2 or ##STR2## R is methyl, ethyl, hydrogen, sodium, potassium or ammonium.

Preparation of 3-hydroxyphenylacetic acid

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Altrip, Germany

Uwe Pressler