Boehringer Mannheim Gmbh

Roche Diagnostics Operations, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Ursula Giesen

Ulrich Neumann

Volker Klemt

Nicholas R Hoyle

Gunter Muller

Kurt Weindel

Peter Wenzig

G&uuml;nter Ziegler

Erna Donnerbauer

The present disclosure relates to a luminescence method of detecting an analyte in a liquid sample comprising marking the analyte with a marker capable of effecting luminescence upon application of excitation energy, wherein reference data descriptive of the luminescence decay is stored in an electronic memory; applying the excitation energy for causing the luminescence; time-resolved measuring of the luminescence over a period of time for acquisition of a measurement signal; reading the reference data from the electronic memory; comparing the measurement signal with the luminescence decay described by the reference data; generating an output signal indicative of the presence of the analyte in the liquid sample using the measurement signal; in case of a mismatch of the measurement signal and the luminescence decay described by the reference data, generating an error signal.

Luminescence method of detecting an analyte in a liquid sample and analysis system

The combination of two mechanisms of detection in a single device yields a method which allows the simple quantification of analyte determinations. Suitable formats and reagent kits are suggested.

Determination of analytes by means of two markers

Electrochemiluminesence assay

Electrochemiluminescence assay

Growing community of inventors

Weilheim, Germany

Ursula Giesen