Perkinelmer Health Sciences, Inc.

Bruker Daltonics, Inc.

Varian, Inc.

Hoefer Pharmacia Biotech, Inc.

Other

Finnigan Corporation

Bear Instruments, Inc.

Agilent Technologies, Inc.

Pharmacia Biotech Inc.

Finnigan Corporation (a Virginia Corporation)

Amersham Biosciences (sf) Corp

Urs Steiner

Felician Muntean

Daniel Robert Marshak

Roy P Moeller

Keith Ferrara

Anthony Chiappetta

Mohammed Rezaul Islam

Lawrence B Jones

Stephen Zanon

Eric R Hungerman

Jochen Franzen

Bert David Egley

Mingda Wang

Nigel P Gore

David Deford

James W Hurst

Terry A Landers

Tim O Lau

Eric G Coates

Hansjorg J Cueni

Thomas S Acampora

Timothy O Lau

Stephen A Sokolow

John R Lewis

Helmut Rother

Hilary Davies

Thinh M Ha

Helene Bredberg-Davies

Charles A Fancher

Richard Alan Flanagan

J Alan Schier

The invention relates to turbo molecular pumps enabling high pumping speed. The disclosure suggests using one or more cage-like rotor stages to optimize pumping speed on vacuum systems with low gas flows and low ultimate pressures. This allows for a smaller motor as well as smaller overall form factor and makes it well suited, in particular, for compact mass spectrometers and desk-top mass spectrometers.

Turbo molecular pump for mass spectrometer

Certain embodiments described herein are directed to ion detectors and systems. In some examples, the ion detector can include a plurality of dynodes, in which one or more of the dynodes are coupled to an electrometer. In other configurations, each dynode can be coupled to a respective electrometer. Methods using the ion detectors are also described.

Ion detectors and methods of using them

Certain embodiments described herein are directed to optical detector and optical systems. In some examples, the optical detector can include a plurality of dynodes, in which one or more of the dynodes are coupled to an electrometer. In other configurations, each dynode can be coupled to a respective electrometer. Methods using the optical detectors are also described.

Optical detectors and methods of using them

Certain embodiments described herein are directed to collision cells that comprise one or more integrated lenses. In some examples, a lens is coupled to two sections of a sectioned quadrature rod assembly, the lens comprising an aperture and a plurality of separate conductive elements disposed each one side of the lens, in which a respective disposed conductive element on one side of the lens is configured to electrically couple to a first, second, third, and fourth pole segments of the sectioned quadrature rod assembly.

Collision cells and methods of using them

The invention relates to mass spectrometers having secondary electron multipliers with series of discrete dynode stages. The invention particularly relates to an operation with extended dynamic measuring range and extended lifetime. The invention is based on not adapting the dynamic measuring range by control of the gain of the trans-impedance amplifier, nor controlling the multiplier operating voltage, which both are usually too slow, but alternating a number of active and passive dynode stages of a discrete dynode multiplier. Each dynode stage is connected to a discrete voltage supply circuit, being able to be de-energized and short-cut; the multiplier gain is feedback-controlled by energizing or short-cutting dynode stages, serially from the end of the multiplier, as a function of a last measured ion signal; and the multiplier has a single trans-impedance amplifier and a single analog-to-digital converter, measuring and digitizing the output current of the last active dynode stage.

Mass spectrometer having multi-dynode multiplier(s) of high dynamic range operation

Certain embodiments described herein are directed to time of flight tubes comprising a cylindrical tube comprising an inner surface and an outer surface, the cylindrical tube comprising an effective thickness and sized and arranged to couple to and support a reflectron assembly inside the cylindrical tube. In some configurations, the cylindrical tube further comprises a conductive material disposed on the inner surface of the cylindrical tube, the conductive material present in an effective amount to provide a field free region for ions when the conductive material is charged.

Time of flight tubes and methods of using them

Certain embodiments described herein are directed to reflectron assemblies and methods of producing them. In some configurations, a reflectron comprising a plurality of lenses each comprising a planar body and comprising a plurality of separate and individual conductors spanning a central aperture from a first side to a second side of a first surface of the planar body is described. In some instances, the plurality of conductors are each substantially parallel to each other and are positioned in the same plane.

Reflectrons and methods of producing and using them

Certain embodiments described herein are directed to rod assemblies such as, for example, quadrupole, hexapole and octupole rod assemblies. In some instances, the rod assemblies include at least one pole comprising an integral fluid path configured to fluidically couple an ion volume formed by the assembly to an outer volume of the assembly to remove fluid within the ion volume to the outer volume while containing ions of a selected mass-to-charge range.

Ion guide or filters with selected gas conductance

Growing community of inventors

Branford, CT, United States of America

Urs Steiner