Urogen Pharma Ltd.

Theracoat Ltd.

Uri Shpolansky

Asher Holzer

Dorit Daniel

Jaime De La Zerda

Yosh Dollberg

Nadav Malchi

Dor Tal

Yossi Yavin

Michael Mullerad

Marina Konorty

Gil Hakim

Holzer Asher

Tal Dor

A hydrophilic biocompatible sustained-release material is disclosed. The material comprises amounts of an ethylene oxide/propylene oxide block copolymer, HPMC, and water, effective to produce a composition of sufficiently low viscosity at room temperature to be injectable into an internal body cavity via a tube inserted within a urinary catheter. At body temperature, the material exhibits a much higher viscosity and will stably adhere to the internal surface of a body cavity. As the material dissolves, a therapeutic agent incorporated therein is slowly released to the body cavity, while the material itself is excreted from the body.

Material and method for treating internal cavities

A hydrophilic biocompatible sustained-release material is disclosed. The material comprises amounts of Pluronic F-127, PEG-400, HPMC and water, effective to produce a composition of sufficiently low viscosity at room temperature to be injectable into an internal body cavity via a tube inserted within a urinary catheter. At body temperature, the material exhibits a much higher viscosity and will stably adhere to the internal surface of a body cavity. As the material dissolves, a therapeutic agent incorporated therein is slowly released to the body cavity, while the material itself is excreted from the body.

Growing community of inventors

Pardes Hana, Israel

Uri Shpolansky