Mead Johnson Nutrition Company

Mjn U.S. Holdings LLC

Ulrike Schulmeister

Udo Herz

Margarete Focke-Tejkl

Ines Swoboda

Rudolph Valenta

Ric Van Tol

Heidrun Hochwallner

Margarte Focke-Tejkl

Eric AF Van Tol

A method for identifying allergenic proteins and peptides. More specifically, a method for identifying allergenic milk proteins and/or peptides including the steps of: providing at least one expression library comprising DNA or cDNA derived from the mammary gland tissue of a lactating cow, expressing at least one protein or peptide encoded by said expression library, determining the binding capacity of said at least one protein or peptide to IgE of at least one serum of an individual who is sensitive to cow's milk, contacting the at least one protein or peptide exhibiting an IgE binding capacity as determined in step c) with basophil cells, eosinophil cells or mast cells and identifying the at least one protein or peptide as being allergenic when said basophil cells, eosinophil cells or mast cells release upon contact with at least one protein or peptide of step d) at least one mediator.

Method for identifying allergenic proteins and peptides

Growing community of inventors

Waldhausen, Austria

Ulrike Schulmeister