Henkel Kommanditgesellschaft Auf Aktien

Henkel Kommanditgesellschaft Auf Aktien (henkel Kgaa)

Ulrich Zeidler

Hinrich Moller

Fanny Scheuermann

Herbert Fischer

Brigitte Hase

Hans-Christoph Wilk

Holger Tesmann

Alfred Meffert

Hermann Hensen

Ludwig Schieferstein

Horst Rutzen

Hinrich Moeller

Thomas Foerster

Jens Conrad

Ulf-Armin Schaper

Eric Sung

Wolfgang Rupilius

Theodor Altenschopfer

Hans Andree

Gunter Jakobi

Fred Schambil

Gunther Konrad

Jochen Kaufmann

Dieter Grodau

Gunther Vogt

Markus Berg

Manfred Budnowski

Albertus Van Wageningen

Soraya Shamsai

Process for the preparation of oil-in-water creams comprising the steps of

Process for the production of oil-in-water creams

Alkyl hydroxyalkyl orthophosphoric acid esters, particularly mixtures thereof, corresponding to the following formula ##STR1## in which R.sup.1 and R.sup.2 represent C.sub.6 -C.sub.22 alkyl groups and R.sup.3 is hydrogen, a group R.sup.1 or a group --CH.sub.2 --CH(OH)--R.sup.2. The esters are prepared by reaction of phosphorus pentoxide with fatty alcohol and reaction of the phosphoric acid partial esters formed with long-chain .alpha.-epoxides. After conversion of the compounds corresponding to formula I, in which R.sup.3 is hydrogen, into the salt form, the new alkyl hydroxyalkyl orthophosphoric acid ester mixtures are particularly suitable as emulsifiers for oil-water emulsion.

Alkyl hydroxyalkyl phosphoric acid esters

Amphoteric and zwitter-ionic phosphate surfactants corresponding to the following formula ##STR1## (a) in which R.sup.1 is a C.sub.6 -C.sub.22 alkyl group, a group R.sup.4 (OC.sub.n H.sub.2n).sub.x --, where n=2 to 4, x=1 to 6, and R.sup.4 is a C.sub.6 -C.sub.22 alkyl group, or a group R.sup.5 --CONH(CH.sub.2).sub.m, where R.sup.5 is a C.sub.5 -C.sub.21 group and m=2 to 4; R.sup.2 is hydrogen; and R.sup.3 is a C.sub.1 -C.sub.4 alkyl group or a group --(C.sub.n H.sub.2n O).sub.x --H or --(C.sub.n H.sub.2n O).sub.x --PO.sub.3 H.sub.2, where n=2 to 4 and x=1 to 6, or

Amphoteric and zwitter-ionic phosphate surfactants

N-substituted polyglycidyl urazole compounds of the general formula ##STR1## in which the radicals R represent a glycidyl radical corresponding to the following general formula ##STR2## wherein R.sub.1 represents hydrogen or an alkyl radical containing from 1 to 4 carbon atoms, or two of the radicals R represent a glycidyl radical of general formula II while the remaining radical R is a radical Z, other than said glycidyl radical, containing carbon, hydrogen and, optionally, heteroatoms, are useful in the treatment of various forms of leukemia.

N-substituted polyglycidyl urazole compounds, processes for their

Oligopeptide derivates corresponding to the general formula

Oligopeptide derivatives, their production and their use as surfactants

Block-copolymeric polyglycol ethers of long-chain 1,2-epoxides and ethylene oxide corresponding to the following general formula

Block-copolymeric polyglycol ethers as solution promoters for

Diglycidyl-substituted pteridine compounds of the general formula: ##STR1## wherein n is the whole number 1 or 2, R.sub.2 and R.sub.2 are the same or different, and are either hydrogen, a hydrocarbon radical, or together form a 5- or 6-membered carbocyclic or heterocyclic ring; processes for their preparation; and compositions and methods for their use as cytostatic agents.

Diglycidyl-pteridine compounds

A 1,3-dialkyl-cyclohexane having the formula: ##STR1## wherein R.sub.1 is a member selected from the group consisting of hydrogen and straight chained or branched C.sub.1 -C.sub.20 -alkyl and R.sub.2 is a straight chained or branched C.sub.1 -C.sub.20 -alkyl; as well as a method of production and its use in cosmetic preparations.

1,3-Dialkyl-cyclohexanes, method of production and method of use in

N-substituted-diglycidyl-isocyanurates having the formula: ##STR1## wherein R represents a hydrocarbon-containing radical selected from the group consisting of alkyl, aryl, aralkyl, alkaryl and cycloalkyl, optionally containing:

Isocyanuric acid derivatives, method of preparation, therapeutic

New cytostatic compounds based on isocyanuric acid derivatives having 2 or 3 epoxide group containing substituents on ring nitrogen atoms, of which at least one differs from a glycidyl, having the formula ##STR1## wherein Oxiranyl is the same or different and has the formula ##STR2## wherein R.sub.1, R.sub.2 and R.sub.3 are the same or different and members selected from the group consisting of hydrogen, alkyl, haloalkyl, hydroxyalkyl and alkoxyalkyl and n in an integer from 1 to 8, with the proviso that if n is 1 in all oxiranyl groups, at least one of R.sub.1 or R.sub.3 is other than hydrogen, and R is a member selected from the group consisting of oxiranyl as defined above, hydrogen, alkyl, alkenyl, hydrocarbon aryl, hydrocarbon aralkyl, hydrocarbon alkaryl, cycloalkyl, and cycloalkenyl, optionally containing substituents. When R.sub.1, R.sub.2 and/or R.sub.3 denote alkyl or substituted alkyl in the oxiranyl radical, the alkyl radicals preferably have from 1 to 4 carbon atoms. The total number of carbon atoms in one oxiranyl radical should not be more than 10. The preparation of these compounds by introducing oxiranyl groups of Formula II and the radical R in known manner into the isocyanuric acid ring is also claimed.

Therapeutic compositions with a cytostatic action containing isocyanuric

Mono- and dicarboxylic acid esters of 1,2-dihydroxyalkanes of the formulae ##STR1## wherein A represents a bivalent radical selected from the group consisting of alkylene having from 1 to 16 carbon atoms, hydroxyalkylene having from 1 to 8 carbon atoms and 1 to 4 hydroxys, alkenylene having from 2 to 18 carbon atoms, alkoxyalkylene having from 2 to 6 carbon atoms, phenylene, alkylphenylene having from 1 to 12 carbon atoms in the alkyl; R.sub.1 represents a member selected from the group consisting of hydrogen and alkyl having from 1 to 12 carbon atoms; R.sub.2 is alkyl having from 10 to 22 carbon atoms; and R.sub.3 represents a member selected from the group consisting of hydroxyalkyl having from 1 to 4 carbon atoms, phenylhydroxyalkyl having from 1 to 4 carbon atoms in the alkyl and haloalkyl having from 1 to 4 carbon atoms; as well as water-in-oil emulsions containing from 1% to 20% by weight of said esters, from 20% to 75% by weight of water and the remainder to 100% by weight conventional oily substances used in cosmetic emulsions.

Esters of 1,2-dihydroxyalkanes as cosmetic emulsifiers and cosmetic

Polycarboxylic acid-2-hydroxyalkyl esters of the formula ##STR1## wherein A is an aliphatic, cycloaliphatic, or aromatic radical which is optionally substituted or interrupted by heteroatoms, and/or optionally substituted by hydroxyl groups, R.sub.1 is hydrogen or an alkyl radical having 1 to 12 carbon atoms, and R.sub.2 is an alkyl radical having 10 to 22 carbon atoms, n.gtoreq.0 and m.gtoreq.2, with the proviso that m.gtoreq.n and the total of n+m.gtoreq.3, and their use as emulsifying agents and cosmetic emulsions containing them.

Polycarboxylic acid-2-hydroxylalkyl esters, their use as emulsifying

Stable, aqueous or aqueous-alcoholic solutions of fat-soluble perfume oils or drugs, containing hydroxyalkyl ester- and/or N-(hydroxyalkyl)-amide-ethoxylates of the formula ##STR1## wherein R.sub.1 and/or R.sub.2 are an alkyl group having 1 to 18 carbon atoms or hydrogen, R.sub.3 is an alkyl group having 1 to 12 carbon atoms or an aryl group, X is an oxygen atom, the group &gt;NH or the group &gt;N--(C.sub.2 H.sub.4 O).sub.m H, and n and m are integers of from 0 to 40, with the proviso that the total of the carbon atoms of R.sub.1 +R.sub.2 is from 6 to 20 and the total of the numbers n+m is a value from 6 to 40.

Stable aqueous or aqueous-alcoholic solutions of fat-soluble perfume

Process for the rinsing of dishes in dishwashing machines having one or several clear-rinsing cycles using an aqueous solution of an adduct of from 2 to 14 moles of ethylene oxide and from 0 to 7 mols of propylene oxide to the monocarboxylic acid ester of an alkanediol with a linear alkane chain of 8 to 20 carbon atoms, and having vicinal hydroxyls, as well as clear-rinsing concentrates for use in the process.

Process and concentrates for clear-rinsing in mechanical dishwashing

A surface-active compound combination for use in textile washing agent compositions consisting essentially of

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Dusseldorf, Germany

Ulrich Zeidler