Gruenenthal Gmbh

Grunenthal Gmbh

Ulrich Jahnel

Klaus Schiene

Babette-Yvonne Koegel

Elmar Josef Friderichs

Guenter Haase

Thomas Tzschentke

Ilona Steigerwald

Johannes Schneider

Babette-Yvonne Kögel

Michel Hamon

Silvia Reinartz

Guenther Haase

Günter Haase

Elmar Friiderichs

Jörg Holenz

Wolfgang Strassburger

The use of tapentadol in the treatment of pain and/or pain chronification in a subject suffering from pain chronification and/or in the treatment of pain and inhibition of pain chronification in a subject suffering from pain and at risk of pain chronification, as well as the use of tapentadol for the treatment or inhibition of migraine.

Method of inhibiting chronification of pain

Combinations of certain analgesics with COX-II inhibitors, related pharmaceutical compositions, including advantageous galenical forms containing these combinations, and the use of such combinations in methods of treatment, in particular for the treatment of pain.

Combination of selected analgesics and COX-II inhibitors

The use of tapentadol (i) in the treatment of pain in a subject suffering from depression and/or from anxiety, and/or (ii) in the treatment or the inhibition of depression or anxiety.

Use of tapentadol for inhibiting and/or treating depression and anxiety

A method of treating or inhibiting, in particular, pain caused by inflammation in a mammal by administering to the mammal an effective inflammatory pain alleviating amount of a (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol compound or a physiologally acceptable salt thereof, such as the hydrochloride or citrate salt.

Method of treating pain caused by inflammation

A method of treating or inhibiting, in particular, pain caused by inflammation in a mammal by administering to the mammal an effective inflammatory pain alleviating amount of a (1R,2R)-3-(2-dimethylaminomethyl-cyclohexyl)-phenol compound or a physiologically acceptable salt thereof, such as the hydrochloride or citrate salt.

Method of inhibiting inflammatory pain

A method of treating or inhibiting, in particular, pain caused by inflammation in a mammal by administering to the mammal an effective inflammatory pain alleviating amount of a (1RS,3RS,6RS)-6-dimethyl-aminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol compound, preferably in the form of a physiologically acceptable salt, such as the hydrochloride.

Combinations of certain analgesics with certain COX-II inhibitors, related pharmaceutical compositions, including advantageous galenical forms containing these combinations, and to the use thereof in methods of treatment, in particular for the treatment of pain.

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Langerwehe, Germany

Ulrich Jahnel