Pulsion Medical Systems Ag

Edwards Lifesciences Iprm Ag

Up-med Gmbh

Philips Medizin Systeme Böblingen Gmbh

Other

Pulsion Medical Systems Se

Fulsion Medical Systems Ag

Iprm Intellectual Property Rights Management Ag

Ulrich J Pfeiffer

Reinhold Knoll

Thorsten M Burger

Daniel Moulas

Frederic Michard

Ulf Borg

Ulf R Borg

Tobias Thomamüller

Matthias Fahle

Stephan Regh

Andreas Becker

Steve Allen

Stephan Joeken

Anna-Luisa Uhlitz

Sebastian Kisban

Matthias F&auml;hle

Christian T&ouml;ns

Wolfgang Kubler

Alwin E Goetz

U Seebauer

Stefan Joeken

Rainer Schmalberger

Norbert Eder

Reinhard Knoll

Manu Malbrain

Frédéric Michard

Tobias Thomamueller

Christian Tons

Matthias Fähle

Matthias FÄHLE

Stefan Fischer

The present invention refers to a blood pressure measuring system () configured to surround a patient's body part (E), comprising pressurization means () for applying pressure to the body part (E), and comprising a kinking-proof shell (), wherein the kinking-proof shell () is arranged so as to be located between the pressurization means () and the body part (E), when the blood pressure measuring system () surrounds the body part (E). The present invention further refers to a method of applying a blood pressure measuring system ().

Blood pressure measuring system comprising a kinking-proof shell

The invention relates to a method for determining blood pressure in a blood vessel, according to which a pulse wave propagation time is caluculated in a measuring operation by means of at least two sensors arranged at a defined distance from one another. The method is characterized in that the blood pressure is calculated using a calibration carried out by means of a compression pressure measurement.

Method for determining blood pressure in a blood vessel and device for carrying out said method

The invention relates to indicator dilution measurements of a central volume (V) with a first site of injection (S) upstream of the central volume (V) a second site of detection (S) of the diluted indicator downstream of the central volume (V), wherein a first additional volume (V) is defined between the first site (S) and the central volume (V) and a first additional branch (B) is defined between the first site (S) and the central volume (V) and wherein a second additional volume (V) is defined between the central volume (V) and the second site (S) and a second additional branch (B) is defined between the central volume (V) and the second site (S) wherein a result of central volumetric parameters are corrected for the first and second additional volumes (V, V) and/or for the first and second additional branches (B, B).

Device for indicator dilution measurements

A blood pressure measuring device includes a flexible element configured to at least partially surround a body part and having a stiffening element configured to stiffen the flexible element; and at least one pressure sensor element attached to the flexible element.

Blood pressure measuring device and method for measuring the blood pressure of a living being

The invention relates to a disposable sensor device () for patient monitoring comprising a sensor () for providing an electric quantity based on a quantity to be detected, a first signal terminal () for providing a tap for the electric quantity, a first supply terminal () for supplying the sensor with an electrical supply quantity, a first connector for accommodating the first signal terminal () and the first supply terminal (), a second signal terminal () for providing a further tap for the electric quantity, and a second connector for accommodating at least the second signal terminal (). The invention further relates to a disposable sensor device for patient monitoring comprising a sensor () for providing an electric quantity based on a quantity to be detected; a first signal terminal () for providing a tap for the electric quantity; a first connector (A) for accommodating the first signal terminal, wherein the first connector (A) is provided with a trimming element (R) which simulates the influence of a selectively attachable first monitoring device () on a measuring of the electric quantity, wherein the trimming element (R) is electrically effective depending on a connector structure of a corresponding further connector (B, C) to be coupled with the first connector (A).

Disposable sensor device and monitoring system with trimming element

An injection system for injecting an injectate fluid into a blood vessel of the patient and for carrying out a blood pressure measurement of a patient. The injection system includes a catheter tube having a first end for penetrating the blood vessel of the patient, and a pressure sensor which is arranged close to a second end of the catheter tube and can sense a pressure of a liquid in the catheter tube as an indication of the blood pressure of the patient.

Blood vessel catheter and injection system for carrying out a blood pressure measurement of a patient

A catheter system includes a flexible, elongated base body adapted to be applied to a vein central-venously and having a base distal end; a fiber-optic probe having a probe distal part; a fiber-optic lumen receiving the fiber-optic probe; and an attachment element configured to avoid a longitudinal displacement of the fiber-optic probe relative to the fiber-optic lumen and configured to detach so as to allow removal of the fiber-optic probe through the longitudinal displacement of the fiber-optic probe relative to the fiber-optic lumen. The attachment element has a connector piece firmly connected to the fiber-optic probe and a counter-piece firmly connected to the base body, wherein the connector piece is connectable to the counter-piece, the connector piece having a shaft piece adjustable lengthwise and disposed on the connector piece so as to vary a length of the connector piece.

Catheter system having an optical probe and method for the application of an optical probe in a catheter system

A device for infusing of at least one medicament includes at least two actuators configured to cause at least two medicaments to be infused; at least one sensor configured to measure a value of at least two parameters; and a controller configured to control the at least two actuators, wherein the controller is programmed to activate the at least two actuators depending on the values of each of the at least two parameters, and wherein the controller is arranged so as to consider a dependency of the at least two medicaments.

Device for infusion of at least two medicaments

The invention relates to a connector system comprising a first connector having a plurality of first contact terminals (E, F, G, J); a second connector having a plurality of second contact terminals, wherein the second contact terminals (A, B, C, D) and the electrical device are arranged such that, while connecting, the first contact terminals come into contact with a first subset of the plurality of second contact terminals in a first connecting stage and while the connecting further proceeds the first contact terminals come into contact with a second subset of the second contact terminals, such that in the first connecting stage an electrical quantity between two of the first contact terminals is detectable which is different from the electrical quantity in an uncoupled condition of the connectors, and in the second connecting stage a further electrical quantity between at least two of the first contact terminals is detectable which is different from the electrical quantity detected in the first connecting stage.

Multilevel connector system

The invention relates to a method and an apparatus for determining the systolic phase interval (SP) of an arterial pressure curve with a starting point (t) of the systolic phase interval (SP) and an end point (tN) of the systolic phase interval (SP) wherein a QT interval is defined as the start of the Q wave and the end of the T wave in the hearts electrical cycle and wherein the determination of the end point (tN) of the systolic phase interval (SP) is restricted to the measured points of arterial pressure which fulfill the condition that the difference in time between the end point (tN) to be determined of the systolic phase interval (SP) and the starting point (t) of the systolic phase interval (SP) is smaller than the QT interval.

Method and apparatus to determine the end of the systolic part of a pressure curve

An apparatus for determining a patient's circulatory fill status is adapted to provide a dilution curve and is capable to derive the ratio between the patient's global end-diastolic volume GEDV and the patient's intra thoracic thermo volume ITTV from the dilution curve. Further, a computer program for determining a patient's circulatory fill status has instructions adapted to carry out the steps of generating the dilution curve on basis of provided measurement data of dilution versus time, deriving the ratio between the patient's global end-diastolic volume GEDV and the patient's intra thoracic thermo volume ITTV from the dilution curve, and determining the patient's circulatory fill status on basis of the ratio between the patient's global end-diastolic volume GEDV and the patient's intra thoracic thermo volume ITTV, when the computer program is run on a computer. A method is also provided.

Dilution apparatus, method and computer program

The invention relates to a device for determining cardiopulmonary volumes and flows of a living being. According to the invention, the evaluation unit () of a transpulmonary measurement arrangement, preferably having a central-vein catheter and an arterial catheter (), is set up, in terms of program technology, for the purpose of taking a possible short-circuit current from the right to the left half of the heart (RL shunt) and/or from the left to the right half of the heart (LR shunt) of the living being into consideration, without the use of a right-heart catheter being required in this connection, or any recourse to pulmonary artery measurement values having to take place at all. In this connection, a model is used as the basis, which contains the function y (system response) corresponding to a dilution curve as the convolution of a disruption function I with several terms that contain characteristic times as model parameters. The terms correspond to ideally mixed volumes or delay elements that are assumed as simplifications for the right atrium (RA), the right ventricle (RV), the pulmonary blood volume (PBV), the extravasal thermal volume (ETV), the left atrium (LA), and the left ventricle (LV).

Device for determining cardiopulmonary volumes and flows of a living being

Determining the transition between systole and diastole is important for pulse contour-analytical determination of hemodynamic, first of all cardiac output. During the temporal progression of arterial pressure P(t) on which pulse contour analysis is based, the transition between systole and diastole appears as a local minimum. This local slump of the pressure curve downward is very short and is often little recognizable in the actually measured curves due to inaccuracies conditioned by measuring techniques. It was also found that the transition between systole and diastole can be more reliably and accurately determined as the site of maximum curvature of function P(t). Consequently, the invention relates to a device having a calculation unit that comprises evaluation means for detecting the site of maximum curvature of function P(t) in a detection area between the maximum and minimum functional value of the pulse cycle as the site of transition between systole and diastole.

Device for determining the transition between systole and diastole

Apparatus, computer system, computer program and storage medium for determining intrathoracic blood volume (ITBV) and other cardio-vascular parameters of a patient by thermodilution measurements. The apparatus includes: temperature influencing means for introducing a traveling temperature deviation to a patient's blood stream, a temperature sensor device for measuring the local temperature of the patient's blood downstream of the temperature influencing means, a computer system adapted to: record local blood temperature measured as a function of time to determine a thermodilution curve, determine global enddiastolic blood volume (GEDV) and intrathoracic thermovolume (ITTV) from the thermodilution curve, determine intrathoracic blood volume (ITBV) as a function of GEDV, ITTV and the airway pressure inside the patient's lungs (P). By determining ITBV not only from GEDV but also a function of ITTV and P enhanced accuracy can be obtained, especially if the patient suffers from pulmonary edema and/or is mechanically ventilated.

Apparatus, computer system and computer program for determining intrathoracic blood volume and other cardio-vascular parameters

An arterially measured pressure signal is continuously read in and temporarily stored in the working memory (RAM). The function p(t) is processed by the central processing unit (CPU), to calculate the heart/time volume PCCO and other hemodynamic parameters. The calculation comprises the following steps: The systemic vascular resistance SVRis calculated for the current pulse period. The stroke volume SVis numerically determined from the pressure values of a pulse period, according to the following equation: with the compliance C()=(MAP&#x2212;CVP)/[SVR&#xb7;&#x3c;dp/dt&#x3e;]&#xb7;&#x192;(). The difference between the mean arterial pressure MAP and the central venous pressure CVP, and the mean incline of the pressure curve in the diastole &#x3c;dp/dt&#x3e;, are re-determined for the current pulse period. The heart/time volume calculated in the current pulse period results from PCCO=SV&#xb7;HR. Therefore, continuous recalibration of the systemic vascular resistance and of the compliance takes place, from the continuously determined pressure measurement data.

Growing community of inventors

Munich, Germany

Ulrich J Pfeiffer