Chelsea Therapeutics, Inc.

Flame Security Sweden Ab

Ulf Vellmar

Leif Svensson

Ingela Fritzson

Helén Tuvesson Andersson

Leif Svenson

Ingrid Hallin

The present invention discloses a composition and the use of the same in fire control applications. The composition comprises a compound of Formula I or any negatively charged deprotonated form thereof or mixtures thereof, a compound of Formula IIa or IIb or any positively charged or tautomeric form thereof or mixtures thereof and a booster. The booster is selected from the group consisting of a hydrophobic component, an amphiphilic component, a rheology modifier and any mixture thereof. Methods for production are also disclosed. 

Aqueous composition comprising phosphorous and nitrogen for general fire control

Compounds of formula (I) are provided, wherein X is CH&#x2550;CH, CHO wherein the oxygen atom is bound to ring B, or OCHwherein the oxygen atom is bound to ring A; Y is hydrogen, straight or branched C1-C6 alkyl or a pharmaceutically acceptable inorganic cation; R1 is ethyl or cyclopropyl; and R2 and R3 are the same or different and are selected from F, Cl, Br, CFand OCF. The compounds are useful for the treatment of autoimmune diseases, inflammatory diseases, organ transplant rejection, and malignant neoplasia. Pharmaceutical compositions containing the compounds, methods of using the compounds, and methods for preparing the compounds are also provided.

Anthranilic acid derivatives

Compounds of formula (I) are provided, wherein X is CH&#x2550;CH, CHO wherein the oxygen atom is bound to ring B, or OCHwherein the oxygen atom is bound to ring A; Y is hydrogen, straight or branched C1-C6 alkyl or a pharmaceutically acceptable inorganic cation; R1 is ethyl or cyclopropyl; and R2 and R3 are the same or different and are selected from F, Cl, Br, CFand OCF. The compounds are useful for the treatment of autoimmune diseases, inflammatory diseases, organ transplant rejection, and malignant neoplasia. Pharmaceutical compositions comprising the compounds, methods of using the compounds, and methods for preparing the compounds are also provided.

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Södra Sandby, Sweden

Ulf Vellmar