Cti Vascular Ag

Ulf Fritz

Marc Gianotti

Michael Jetter

Sabina Silva

Andreas Bodmer

Martin Rickert

Stefan Richter

Adrienne Müller

Margeta Dragana

Johannes Kuhlicke

Adila Rapkic Fazlija

Valentin Nickel

Lucien Pistol

Christopher Weisser

Dragana Margeta

The present disclosure is related to inorganic, biocompatible material compositions for bioactivatable devices, devices, and products comprising transition metal chalcogenides, such as molybdenum sulfides, that can be converted in vivo from a non-bioactive state to a bioactive state upon exposure to physiological conditions, wherein the bioactivated transition metal chalcogenide derivatives, such as molybdenum sulfide derivatives, exhibit copper-chelating activities. Various methods for the application of these compositions for enhancing biocompatibility and reducing or modulating copper-dependent biological reactions are provided.

Bioactivatable devices and related methods

In accordance with the present disclosure there is provided an angioplasty catheter system and method for using such angioplasty catheter system that facilitates controllably delivering focalized pressure to complex lesions. The angioplasty catheter comprises an elongated member having a proximal end, a distal end, and at least one lumen extending at least partially through the elongated member, and an inflatable member proximally affixed to the elongated member adjacent to the distal end and in fluid communication with the at least one lumen, the inflatable member having a radius R and including at least two lobes (), the at least two lobes separated from each other by one or more waist portion () defined by two legs () and a waist portion length () such that upon pressurization, radial stress around the waist portion is directed away from the vessel wall and focalized into the lesion at an angle about perpendicular to the legs () of the upper and lower base of the waist portion () creating variable directional forces from to () to (') resulting in the preferential formation of lesion fractures at the waist of the inflatable member.

Angioplasty balloon catheter for treating vascular disease

Growing community of inventors

Bargen, Switzerland

Ulf Fritz