Gedea Biotech Ab

Adenovir Pharma Ab

Ulf Ellervik

Olov Sterner

Helena Strevens

Sophie Manner

Anders Carlsson

Nils-Olof Lindberg

Karolina Aplander

Annette Säfholm

The present invention concerns a pharmaceutical composition comprising glucono-δ-lactone, which is suitable for use in the treatment of vaginal microbial infections.

Vaginal tablet formulation

Pharmaceutical compositions and methods of using said pharmaceutical compositions are provided herein. A method of preventing preterm birth in a pregnant individual is also provided, said method comprising administering to said individual a pharmaceutical composition comprising a compound of Formula XX or a lactone thereof of formula XIX or XXI and preventing said preterm birth by said administration.

Gluconic acid derivatives for use in the treatment and/or prevention of microbial infections

The present invention relates to a pharmaceutical formulation for vaginal administration, wherein the formulation comprises a pharmaceutical acceptable excipient and glucono &#x3b4;-lactone, wherein the glucono &#x3b4;-lactone is present in an amount of 5 to 99 wt % of the formulation. The invention also relates to a pharmaceutical formulation according to the invention for use in the prevention or treatment of a urogenital fungal infection. Furthermore, the invention relates to glucono &#x3b4;-lactone (formula (III)), for use in the in the prevention or treatment of a fungal infection.

Glucono delta-lactone for treatment of vaginal fungal infections

The present invention concerns a pharmaceutical composition comprising a compound of Formula I for use in the treatment and/or prevention of microbial infections. Furthermore, the present invention concerns a method for prevention and/or reduction of biofilm formation.

Herein are disclosed novel compounds according to Formula (I) and aggregates comprising such compounds. These aggregates are useful to treat and prevent ocular infections caused by a vims, which virus binds to terminal sialic residues present on the cell surface of the cell to be infected by the virus. 

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Loddekopinge, Sweden

Ulf Ellervik