Korea Atomic Energy Research Institute

Ul Jae Park

Hyon Soo Han

Hyeon Young Shin

Jin Joo Kim

Sang Mu Choi

Kwang Jae Son

So-Young Lee

Jun Sig Lee

Jae Cheong Lim

Kang Duk Jang

Soon Buk Hong

Woon Kap Cho

Jong Sub Lee

Soon Bog Hong

Kyeong Deuk Jang

Sung Soo Nam

Kwon Mo Yoo

Eun Ha Cho

Provided is a novel compound capable of being usefully used to diagnose and treat prostate cancer by labeling a radioisotope on a bombesin derivatives capable of selectively targeting a target material over-expressed in tumor cells in order to develop an effective diagnose and treatment method of diseases associated with prostate cancer.

GRP-R agonistic 177-lutetium-labeled bombesin derivatives for diagnosis and treatment of prostate cancer

Disclosed is a novel adsorbent for use in aMo/Tc generator, which is a medical diagnostic radioisotope generator, and in aW/Re generator, which is a therapeutic radioisotope generator. The adsorbent composed of sulfated alumina or alumina-sulfated zirconia exhibits adsorption capacity superior to that of conventional adsorbents, and is stable and is thus loaded in a dry state in an adsorption column so that the radioisotopeMo orW can be adsorbed. Thus, it is possible to miniaturize the column, and such a miniaturized column is small, convenient to use, and highly efficient, and extracts a radioisotope satisfying the requirements for pharmaceuticals, and thus can be useful for radioisotope generators extractingTc orRe.

Adsorbents for radioisotopes, preparation method thereof, and radioisotope generators using the same

A method for distillation of sulfur for preparing radioactive phosphorous nuclide includes the steps of: charging powdered sulfur into a target tube designed to have an upper and a bottom neck; degassing the target tube to form a vacuum therein, followed by heating the upper neck to seal the target tube; irradiating neutrons into the sealed target tube to produce radioactive phosphorous nuclide; heating the distillation zone to distill the remaining unreacted sulfur; and cleaving the target tube at the bottom neck to separate the distillation and the cooling zone from each other, the separated zones containing the radioactive phosphorous nuclide and the unreacted sulfur, respectively, whereby the radioactive phosphorous nuclide of high purity can be prepared while the sulfur can be recovered at high efficiency.

Method for distillation of sulfur for the preparing radioactive phosphorous nuclide

A radiation source assembly and a connector press used in producing such assemblies. In the radiation source assembly, each of the cap connector and the female connector is provided with internal round threads on its pigtail fitting hole, thus engaging with the large-diameter coil of the pigtail at the internal round threads through a thread engagement prior to a compression process of the press. The assembly also allows a person to know whether both ends of the pigtail fully reach desired points within the two connectors, thus securing a precise compressing target portion during a compression process of the press. The inserted lengths of the pigtail relative to the two connectors are maximize accomplishing a desired linearity of the assembly. In the assembly, a target biasing spring is provided on the capsule lid and allows the disc targets within the source capsule to effectively maintain a desired condition as point sources regardless of the number of targets. The connector press of this invention accomplishes a desired compression locking of the source capsule to the pigtail by simultaneously compressing the capsule at regularly and angularly spaced points through a multi-point compressing process, thus accomplishing a desired linearity of the radiation source assembly.

Radiation source assembly and connector press used in producing such assemblies

Growing community of inventors

Daejeon, South Korea

Ul Jae Park