Amylin Pharmaceuticals, Inc.

Astrazeneca Pharmaceuticals LP

Reshape Medical, Inc.

Seaspine, Inc.

Tyler John Holschlag

Stephen Sosnowski

Daniel Eugene Kincade

Philip Simpson

David G Matsuura

Christopher Marden John Cain

Phillip A Estepa

William J Casey

Reynaldo B Halili, Jr

Victor Wei-Chung Chang

Zebulon Allen Yoder

Daniel E Kincade

One or more connectors insertable into a surgical incision to couple rods together. The connector may include one or more bushings or joints to displace the one or more rods in one or more directions to a variety of orientations. One or more fasteners and/or bushings may be used to engage the one or more rods.

Implantable universal connector

According to features of the present disclosure, a gastric space filler device and methods effective for reducing stomach volume are disclosed. A gastric space filler comprising at least one inflatable space filler and a sleeve to prevent leakage out of the gastric space filler device is disclosed. The gastric space filler device may be inflated with an insufflation fluid and with mineral oil, which further has the effect of reducing leakage. Delivery systems and methods for inserting a gastric space filler device into a patient are also disclosed. Sheaths and methods for covering a gastric space filler device during delivery into a patient are also disclosed.

Gastric space filler device, delivery system, and related methods

The present invention provides a device for injection of formulations into a patient. In one embodiment the injection is sub-cutaneous. The device is convenient for injecting viscous formulations that would otherwise clog conventional injection devices, for example formulations containing microspheres, suspensions, and other viscous substances. Generally, the device features a needle for piercing the skin, an internal chamber for holding and transmitting fluid, a plunger for applying pressure to the internal chamber, a switch for triggering withdrawal of the needle, a sheath at least partially encompassing the needle and having a flow path within the sheath, and a spring that expands when the switch is triggered, and which thereby at least partially withdraws the needle from the sheath.

Formulation delivery device

Pen injection devices () and methods of using a pen injection device are disclosed. Pen injection devices include a sterile dual transfer spike assembly () including a dual transfer spike defining a fluidic pathway; a first cartridge assembly () including a first cartridge () containing a first substance; a second cartridge assembly () including a second cartridge () containing a second substance; a plunger rod () translatable in a first direction; and a biasing mechanism () configured to bias the plunger rod in a second direction opposite the first direction. Methods of using a pen injection device having a first container, a second container, a plunger rod, and a biasing mechanism include activating the pen injection device, thereby creating a fluidic pathway between the first container and the second container; and translating the plunger rod at least once, thereby transferring a first substance from one container to the other container to mix with a second substance.

Pen injection device and method of using same

A gastric space filler device effective for reducing stomach volume comprises at least one inflatable space filler and a sleeve to prevent leakage out of the gastric space filler device. The gastric space filler device may be inflated with an insufflation fluid and with mineral oil, which further has the effect of reducing leakage. Delivery systems and methods are effective for inserting a gastric space filler device into a patient. The gastric space filler device may be provided with sheaths and methods for covering the gastric space filler device during delivery into a patient.

Growing community of inventors

Carlsbad, CA, United States of America

Tyler John Holschlag