Syntheon 2.0, LLC

Syn Variflex, LLC

Tyler Bond

Matthew A Palmer

Derek Dee Deville

Thomas O Bales, Jr

William Thomas Bales

Eric Petersen

Richard Cartledge

M Sean McBrayer

Michael Walter Kirk

Matthew Weger

An external LAA exclusion clip comprises a clipping assembly comprising first and second opposing clip struts each of the clip struts having a tissue-contacting surface and first and second bias surfaces, a bias assembly connecting the first clip strut to the second clip strut to align the first and second clip struts in a strut plane passing through the tissue-contacting surface. The bias assembly comprises at least one first bias spring connected to the first bias surface of the first clip strut and to the first bias surface of the second clip strut and at least one second bias spring connected to the second bias surface of the first clip strut and the second bias surface of the second clip strut. The first bias spring and the second bias spring are configured to permit movement of the first and second clip struts in the strut plane.

Left atrial appendage clipping device and methods for clipping the LAA

A catheter comprises a heater control supplying power, a handle, a base catheter with lumen and comprising a proximal section and a distal segment, and a variable stiffness element. The element comprises a heater connected to the heater control, coiled at least at the distal segment, and comprising a shaft portion of a first metallic conductive material and a heater portion of a second metallic conductive material. A jacket is disposed about the heater portion. A variable flex sub-assembly between the catheter and jacket comprises a non-conducting braid and a binding material. Without power, the binding material is stiffened. Responsive to heating of the binding material, the binding material softens to increase flexibility of the variable flex sub-assembly at least at the distal segment. Responsive to removing power, the binding material cools and stiffens to decrease flexibility of the variable flex sub-assembly at least at the distal segment.

Thermally controlled variable-flexibility catheters and methods of manufacturing same

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Miami, FL, United States of America

Tyler Bond