Dermavant Sciences Gmbh

Other

Tyler Andrew Davis

Nicholas Calandra

Ravinder Reddy Sudini

Ian Paul Andrews

Kelly Pisane

Emily Despeaux

Chris Bostick

Alice Han

William Mandler

The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.

Process for preparing tapinarof

A pipette tip orienting apparatus includes a hopper adapted for receiving one or more pipette tips. A first alignment comb is inserted thorugh the hopper for orienting pipette tips inside the hopper. A second alignment comb is inserted through the hopper for orienting the pipette tips for delivery to a pipette tip rack. The first and second alignment combs are positioned perpendicular to one another through the hopper. Pipette tips are delivered to wells in a pipette tip rack by removing the alignment combs sequentially from the hopper.

Method and apparatus for orienting pipette tips

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Research Triangle Park, NC, United States of America

Tyler Andrew Davis