Daiichi Pharmaceutical Co., Ltd.

Daiichi Seiyaku Co., Ltd.

Tutomu Ebata

Naoki Ohta

Toshifumi Akiba

Tatsuru Saito

Sadahiro Shimizu

Keiichi Hirai

Toshiaki Tojo

Toshihiro Fujiwara

Production process of cyclic compound

This invention is to provide a compound represented by the following formula (I) and a compound represented by the following formula (II) useful as an antibacterial agent which is obtained by the compound of formula (I), and also to provide a novel synthetic process for the inexpensive, short-step and industrially advantageous production thereof. ##STR1##

Propoxybenzene derivatives represented by the following formula ##STR1## wherein Ra represents a nitro group, an amino group which may have a protecting group or an --NHCH.dbd.C(COO--C.sub.1-6 -Alkyl).sub.2 group, Rb represents a hydrogen atom, a protecting group for the hydroxyl group or a substituted sulfonyl group and Xa and Xb, which may be the same or different, each represents a halogen atom, and processes for preparation thereof are disclosed. These derivatives are useful in preparing antibacterial agents.

Propoxybenzene derivatives and process for preparing the same

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Tokyo, Japan

Tutomu Ebata