Kyoto University

Nitto Pharmaceutical Industries, Ltd.

Noster Inc.

Marukome Co., Ltd.

Tsuyoshi Goto

Teruo Kawada

Jun Ogawa

Shigenobu Kishino

Yasunori Yonejima

Nobuyuki Takahashi

Keiji Nakata

Takashi Hirata

Tatsuya Sugawara

Hidekazu Kim

Si-Bum Park

Noriyoshi Ichijo

Hsin-Yi Chi

Haruya Takahashi

The present invention provides production of hydroxylated fatty acid by a hydration reaction using a novel enzyme derived fromand using fatty acid as a substrate, and further, a production method of oxo fatty acid by an enzyme reaction or chemical oxidation reaction using the hydroxylated fatty acid as a substrate. In addition, a valuable novel rare fatty acid obtained by such production method is also provided.

Method for producing rare fatty acid using novel enzyme, and novel rare fatty acid

The invention provides a metabolism improving agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the metabolism improving agent.

Metabolism-improving agent comprising rare fatty acid

The invention provides a novel PPAR&#x3b1; activator, a pharmaceutical composition, a food or a drink, a food additive, a supplement and a method of producing these products. The PPAR&#x3b1; activator includes an extract of a koji that contains 9-hydroxy-10,12-octadecadienoic acid (9-HODE: 10E, 12E) or an active fraction of the extract, as an active ingredient.

PPAR&#x3b1; activator, pharmaceutical composition, food and drink, food additive, supplement and method of manufacturing the same

The present invention provides a metabolism improving agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the metabolism improving agent.

The present invention provides a metabolism improving agent comprising an oxo fatty acid having 18 carbon atoms and a carbonyl group at the 10- or 12-position, and/or a hydroxy fatty acid having 18 carbon atoms and a hydroxyl group at the 10- and/or 12-position(s), and use of the metabolism improving agent as a food, a pharmaceutical product and the like.

Growing community of inventors

Kyoto, Japan

Tsuyoshi Goto