Kaneka Corporation

Kanegafuchi Kagaku Kogyo Kabushiki Kaisha

Tsutomu Okuyama

Satoshi Takata

Kouji Fujita

Kouichiro Tanaka

Nobutaka Tani

Akira Kobayashi

Shigeo Furuyoshi

The present invention relates to a cellulosic particle body comprising interconnected cellulosic small particles with small interparticle spaces and to a method of producing said cellulosic particle body which comprises dispersing cellulosic small particles in an alkaline medium and contacting the resulting suspension with a coagulating solution. In this specification, the above technology will be referred to as the first invention.

Cellulosic particles, spherical object comprising cross-linked polymer particles, and adsorbent for body fluid purification

The present invention has its objects to provide an adsorbent capable of efficiently adsorbing and removing LDL and VLDL from various lipoprotein-containing solutions, as well as a lipoprotein adsorber in which the adsorbent is used. This invention is related to a lipoprotein adsorbent which comprises a water-insoluble carrier having, on at least one part of the surface of the carrier, at least one group (other than p-nitrobenzoic acid) selected from the group consisting of groups represented by the general formula, and groups represented by the general formula.

Lipoprotein adsorbent and lipoprotein adsorber made with the use of the same

A process for steam-sterilizing an adsorbent for use in extracorporeal circulation treatment comprising a water-insoluble support and a sulfated polysaccharide immobilized on the support, characterized by sterilizing the adsorbent in an aqueous medium maintainted at pH 5 to 9, whereby the sulfated polysaccharide is prevented from releasing from the support and being deactivated. When the water-insoluble support/sulfated polysaccharide adsorbent is packed in a column with an aqueous buffer solution having a pH 5 to 9 to provide an adsorption column for use in extracorporeal circulation treatment, release and deactivation of the sulfated polysaccharide are prevented and the column can be stored for a long term.

Sterilization of adsorbent and column having improved storability

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Kobe, Japan

Tsutomu Okuyama