National Defense Medical Center

Tsung-Hsun Liu

Niann-Tzyy Dai

Ming-Kung Yeh

Eric Frank Adams

Allan Gerald Arthur Coombes

Provided herein are skin substitutes suitable for use in a living subject for purpose of repairing damaged tissues, methods of producing the skin substitutes and their uses. A biocomposite membrane comprising poly(&#x3b5;-caprolactone) (PCL) and at least one material selected from collagen and gelatin is provided. In one embodiment, the biocomposite is a 2-component membrane of PCL and gelatin. In another embodiment, the biocomposite is a 3-component membrane of PCL, collagen and gelatin. The bio-composite membrane may be used directly in vivo as a wound dressing, or as a support for cell growth on each side of the membrane to produce an in vitro cultivated artificial skin for future in vivo and/or in vitro applications.

Growing community of inventors

Taichung, Taiwan

Tsung-Hsun Liu