Other

Yoshitomi Pharmaceutical Industries, Ltd.

Mitsubishi Pharma Corporation

Welfide Corporation

Tsuneo Fujii

Tadashi Mishina

Koji Teshima

Tomonori Imayoshi

Kenji Chiba

Atsushi Sakai

Rumiko Masuda

Toshihiro Baba

Medicinal compositions which can be processed into solutions and are useful in inhibiting rejection reactions against the transplantation of organs or bone marrow, in the maintenance immunotherapy therefor or in treating autoimmune diseases, characterized by containing 2-amino-2-&lsqb;2-(4-octylphenyl)ethyl&rsqb;propane-1,3-diol or pharmaceutically acceptable acid-addition salts thereof and cyclodextrins as a stabilizer optionally together with saccharides, if required.

Pharmaceutical composition

An aqueous liquid preparation, which has a pH of from 3 to 5 and comprises (R)-(&minus;)-3-methyl-3-methyl -sulfonyl-1-(1H-1,2,4-triazol-1-yl)-2-&lsqb;4-(trifluoromethyl)phenyl&rsqb;butan-2-ol or a pharmaceutically acceptable salt thereof; and an injection for intravenous administration comprising the aqueous liquid preparation.

Water-base liquid preparation

An external preparation for topical administration which aims at inhibiting rejection reactions at organ or bone marrow transplantation or treating autoimmune diseases or allergic diseases and contains as the active ingredient 2-amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol or a pharmaceutically acceptable acid addition salt thereof.

External preparation of 2-amino-2-(2-(4-octylphenyl)ethyl) propane-1,3-diol or pharmaceutically acceptable salts thereof for topical administration

Topical administration of

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Fukuoka, Japan

Tsuneo Fujii