Shiseido Company, Limited

Other

Takeda Chemical Industries, Inc.

Tsunao Magara

Koji Kobayashi

Hirotada Fukunishi

Masazumi Watanabe

Masahiro Tajima

Yoshiharu Tsuji

Eriko Takeoka

Yoshihisa Sato

Tetsuji Hirao

Chika Hamada

Yosuke Nakazawa

Kohya Shiratori

Disclosed is a hair revitalizing tonic composition containing a dimethylpropanediol derivative of the formula:

Hair revitalizing tonic composition containing a 2,2-dimethylpropanediol compound and use thereof

A &lsqb;6-(substituted-methyl)-3-cyclohexenyl&rsqb;formamide derivative or a salt thereof expressed by the following Formula (I):

&lsqb;6-(substituted-methyl)-3-cyclohexenyl&rsqb; formamide derivative, hair growth promoter and external composition for skin

The invention relates to a hair revitalizing tonic composition containing, as an active ingredient, at least one lipid derivative of the general formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and Y are as defined in the specification, and a and b are 0 or 1, as well as its use. Thus, there is provided a hair revitalizing tonic composition having an excellent hair loss prevention and hair revitalizing effect and, moreover, an excellent dandruff and itchy scalp prevention effect.

Hair revitalization tonic composition containing a lipid derivative and

A quinazolinone derivative or a salt thereof expressed by the following Formula (I); ##STR1## wherein each of A and B is R.sup.1 or --(CH.sub.2).sub.n -NR.sup.2 R.sup.3 ; wherein R.sup.1 represents a hydrocarbon group of C.sub.10-30 ; wherein R.sup.2 and R.sup.3 individually represent a hydrogen atom, a lower alkyl group, a phenyl group, or a benzyl group, or together represent a heterocyclic ring having 3-7 members; and n represents an integer of 1-5; wherein when A is R.sup.1, B is --(CH.sub.2).sub.n -NR.sup.2 R.sup.3 and when A is --(CH.sub.2).sub.n -NR.sup.2 R.sup.3, B is R.sup.1 ; and wherein R.sup.4 is selected from the group consisting of a hydrogen atom, a halogen atom, a lower alkyl group, a lower acyl group, a nitro group, a cyano group, an amino group, a lower alkoxycarbonyl group, a lower alkylamino group, a lower alkoxy group, a lower acyloxy group, a carbamoyl group, a lower alkylcarbamoyl group, and a lower acylamino group. The quinazolinone derivative or the salt thereof has excellent hair growth and regrowth promoting effects, which are useful for care, improvement or prevention of hair loss in mammals and, in particular, in humans.

Quinazolinone derivative, hair growth promoter and external composition

Anthranilic acid ester derivatives having the general formula (I): ##STR1## wherein R represents as alkyl group having 1 to 3 carbon atoms substituted with a pyridyl group or a furanmethyl group. These anthranilic acid ester derivatives have a remarkable antiinflammatory and analygetic effect and a high endermic permeability and, therefore, is suitable for use as an antiinflammatory and analgetic agent.

Anthranilic acid ester derivatives and antiinflammatory and analgetic

Growing community of inventors

Tokyo, Japan

Tsunao Magara