Eyenovia, Inc.

Iantrek, Inc.

Wavetec Vision Systems, Inc.

Other

Novartis Ag

Transcend Medical, Inc.

Trascend Medical, Inc.

Tsontcho Ianchulev

Bernard L Ballou, Jr

Mark Packer

Russell John Mumper

Luke W Clauson

Thomas A Silvestrini

Steven John

John Hilbert Hebrank

Charles Eric Hunter

Joshua Richard Brown

J Sid Clements

Edward Y Koo

Jurgen Klaus Vollrath

James Thornhill Leath

Nathan R Faulks

Thomas J Lindner

Bradley G Johnson

Arthur Henry Tew

Troy Elliott

Walter M Fierson

Phillip E Russell

Richard S Lilly

Syed Khizer Rahim Khaderi

Michael Schaller

David Lari

Bernard L Ballou

The present invention includes and provides a method of delivering a medicament to an eye of a subject in need thereof a solution, the method comprising: (a) providing droplets containing the medicament with a specified average size and average initial ejecting velocity, and (b) delivering the medicament to the eye, where the droplets deliver a percentage of the ejected mass of the droplets to the eye.

Ophthalmic drug delivery

A method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use and a device for droplet ejection includes a fluid delivery system capable of delivering a defined volume of the fluid in the form of droplets having properties that afford adequate and repeatable high percentage deposition upon application. The method and device include a housing, a reservoir disposed within the housing for receiving a volume of fluid, an ejector mechanism configured to eject a stream of droplets having an average ejected droplet diameter greater than 15 microns, the stream of droplets having low entrained airflow such that the stream of droplets deposit on the eye of the subject during use.

Drop generating device

A system for preparation of an implant and ab interno insertion of the implant into an eye including a handle having one or more actuators and an elongated shaft having an outer sheath and an elongate member positioned within a lumen of the tubular outer sheath. The system includes a recess sized for holding a patch of material fixed relative to the handle and a cutting member movable relative to the handle and to the recess. The cutting member cuts the patch of material into an implant as the cutting member moves towards a cutting configuration. The implant, once cut, is axially aligned with the lumen of the tubular outer sheath. The inner elongate member is movable relative to the tubular outer sheath to advance the implant into a deployment position in the lumen of the tubular outer sheath for delivery into the eye. Related devices and methods are provided.

Implantable biologic stent and system for biologic material shaping, preparation, and intraocular stenting for increased aqueous outflow and lowering of intraocular pressure

Implantable biologic stent and system for biologic material shaping and preparation in the treatment of glaucoma

The present invention includes and provides a method of delivering a medicament to an eye of a subject in need thereof a solution, the method comprising: (a) providing droplets containing the medicament with a specified average size and average initial ejecting velocity; and (b) delivering the medicament to the eye, where the droplets deliver a percentage of the ejected mass of the droplets to the eye.

Devices and methods to remove trabecular meshwork to treat glaucoma and other conditions which may not utilize cutting elements when stripping the trabecular meshwork. The trabeculorhexis parts tissue by applying non-cutting shear and tension to the tissue to disinsert the tissue from its attachments. Reducing or eliminating the need for sharp cutting implements in the eye reduces the likelihood of incisional bleeding, iris and scleral tissue maceration and further inadvertent tissue damage of the gonio structure of the eye. In another aspect, a cutting element may be used to form a circumferential slit in a wall of Schlemm's canal in conjunction with removal of trabecular meshwork or independently.

Methods and devices for increasing aqueous drainage of the eye

Embodiments of the present specification provide surgical methods and apparatuses to deploy at least one stent through an optic nerve sheath in order to maintain an opening/fenestration for intracranial fluid egress. The surgical method creates a fenestration, an opening, a slit, or a hole, through an optic nerve sheath of a human patient. The fenestration is created in a minimally invasive manner using an applicator, such as an endoscopic visualization apparatus, that includes a stent or shunt for deploying through the fenestration. The presently disclosed specification is indicated to treat papilledema and/or intracranial hypertension and to deliver therapeutic compositions through the optic nerve sheath.

Methods and systems for treating intracranial hypertension and related indications using an optic nerve stent or shunt

Systems, methods, and computer-readable storage media for applying an adhesive film to the sole of shoes. Application of a portion of the adhesive film can be performed by receiving a shoe on top of the adhesive film, which in turn is above a plate and compressible pins. Upon receiving the shoe, the plate is raised or lowered, and the compressible pins mark the perimeter of the sole of the shoe. The adhesive film is cut in a sole-shaped pattern due to the height differentiation, resulting in a sole-shaped portion of the adhesive film being adhered to the sole of the shoe.

System and method for adhesive application of a customized sole-shaped pad

Growing community of inventors

San Mateo, CA, United States of America

Tsontcho Ianchulev