Ben-Gurion University of the Negev Research and Development Authority

Hadasit Medical Research Services and Development Ltd.

Tsiona Elkayam

Yaron Ilan

Smadar Cohen

Eyal Shteyer

Gadi Lalazar

Ami Ben-Ya'Acov

Ami Ben-Yaakov

The present invention relates to methods for the treatment of hepatic disorders in a subject in need thereof. More specifically, the methods of the invention are based on the administration, preferably, systemic administration, of a therapeutically effective amount of at least one biocompatible alginate biomaterial, any modification thereof and any combination thereof. The invention further provides methods for sustaining serum albumin levels, and/or reducing serum AST and ALT, in subjects suffering from hepatic disorder. Still further, the invention provides methods for reducing apoptosis and inducing cell proliferation in a damaged liver tissue of a subject suffering of hepatic disorder, using the alginate biomaterial described by the invention.

Alginate biomaterials for the treatment of hepatic disorders

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Mobile Post Negev, Israel

Tsiona Elkayam