Toshiba Tec Kabushiki Kaisha

Kabushiki Kaisha Toshiba

Toshiba Corporation

Irm LLC

Other

Novartis Ag

Toshiba Corp Oration

Irm Llc, a Delaware Limited Liability Company

Truc Ngoc Nguyen

William Su

Baogen Wu

Katie Kuwata

Tao Jiang

Xiaohui He

Kunyong Yang

Xuefeng Zhu

Yun He

Peter Hn Tran

David Archer Ellis

Hong Liu

Pierre-Yves Michellys

Badry Bursulaya

Bei Chen

Wei Pei

Kelli L Kuhen

Jianxin Wang

Dean Paul Phillips

Michael Lee Yeung

Louis M Ormond

Xing Wang

Yongping Xie

Robert Epple

Ayako Honda

Rodrigo Rodriguez

Thomas H Marsilje, Iii

Vincent Wu

Ha-Soon Choi

Tony T Quach

Mihai Azimioara

Duncan Shaw

Casey Jacob Nelson Mathison

Zhicheng Wang

Barun Okram

Victor Ivanovich Nikulin

David H Woodmansee

Hasnain Ahmed Malik

Mike Yeung

Philip Lam

Sejal Patel

Thomas Lau

John X Garred

Chen Yi Huang

Yonghui Ge

Zhaobo Gao

Yuncheng Li

Susan L Mizer

Emily Tucker

Declan Hardy

Yiping Shen

Fabio Meier

Rodrigo A Rodriguez

Chen Huang

The invention relates to heterocyclic compounds of the formula (I) in which all of the variables are as defined in the specification; capable of modulating the activity of CFTR. The invention further provides a method for manufacturing compounds of the invention, and its therapeutic uses. The invention further provides methods to their preparation, to their medical use, in particular to their use in the treatment and management of diseases or disorders including Cystic fibrosis and related disorders.

N-(pyridin-2-yl)pyridine-sulfonamide derivatives and their use in the treatment of disease

The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, c-ros oncogene (ROS), insulin-like growth factor (IGF-1R), and/or insulin receptor (InsR) or a combination thereof. 

Compounds and compositions as protein kinase inhibitors

The invention relates to triazine and pyrimidine derivatives having Formula (1) or (2), and methods for using such compounds. For example, the compounds of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, c-ros oncogene (ROS), insulin-like growth factor (IGF-IR), and/or insulin receptor (InsR) or a combination thereof. 

Compounds and compositions as kinase inhibitors

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).

Compounds and compositions as inhibitors of cannabinoid receptor 1 activity

Selective rerouting of document processing jobs is disclosed. A printer driver first converts electronic document data is into a device compatible format and assigned a unique document ID. The printer driver then determines a set of network devices, such as document processing devices, that are participating in the performance of received document processing jobs. The converted document data is then divided into portions and one or more portions are then sent to each of the participating network devices. One of the devices is then selected as the output device, whereupon the output device broadcasts/multicasts a request for processed data portions from each of the other network devices. The received portions are then recombined, and released for further processing in accordance with the received document processing job.

Rerouting of document processing jobs

The invention provides compounds having Formula Ia, or a pharmaceutically acceptable salt thereof, wherein R, R, R, Rand Y are as defined in the specification; as well as pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).

A system and method for printing a file on a remote printer via an electronic message. A personal electronic device transmits an electronic message requesting a listing of available electronic files. The personal electronic device then receives an electronic message in response to the request containing a list of available electronic files. At least one electronic file is then selected from among the listing of available files. The personal electronic device then receives, from the remote computer, an electronic message containing the selected electronic file. The personal electronic device then forwards the message containing the file to an image processing device.

System and method to perform mobile printing from handheld devices

The subject application is directed to a mobile document processing system and method. A request for a transient address corresponding to mobile document processing operations is first received from an associated user. Upon receipt of the request, a transient address is generated corresponding to the associated user. Transient address data is then generated for routing electronic documents in accordance with a received document processing request. A document processing request is then received corresponding to a request for the performance of processing of at least one electronic document. The at least one electronic document is then routed to an associated document processing device, data storage device, or facsimile device corresponding to the transient address. The associated document processing device, data storage device, or facsimile device then commences a document processing operation according to the received document processing request. Upon the occurrence of a selected event, the transient address is deleted.

System and method for routing electronic documents for processing via transient e-mail addressing

A method for directing customers to a business establishment. A query is received from an associated user representing a desired purveyor of a selected good or service in a selected geographic area. Data is then secured representing a set of purveyors of the desired goods or services in the selected geographic area. Business activity data is then acquired corresponding to business activities for each of the purveyors in the set. A business activity level signal is then generated to represent the level of business activity for each purveyor in the set. This data is then communicated to the associated user.

System and method for selecting a business location, wherein the business location has an activity level indicator

A system and method for selective rerouting of document processing jobs is provided. A printer driver first converts electronic document data is into a device compatible format and assigned a unique document ID. The printer driver then determines a set of network devices, such as document processing devices, that are participating in the performance of received document processing jobs. The converted document data is then divided into portions and one or more portions are then sent to each of the participating network devices. One of the devices is then selected as the output device, whereupon the output device broadcasts/multicasts a request for processed data portions from each of the other network devices. The received portions are then recombined, and released for further processing in accordance with the received document processing job.

System and method for rerouting of document processing jobs

The subject application is directed to a system and method for generating gift cards. Image data representing gift card formats is first generated on an associated display. A gift card is then selected and text data is received representing text associated with the selected gift card. Gift amount data is then received representing a fungible value associated with the selected gift card. Charge data associated with a cost associated with the gift amount is then received. Encoded data, corresponding to the gift amount, is then generated. Thereafter, a tangible gift card is generated in accordance with the selected gift card format and the received text. In accordance with one embodiment of the subject application, the encoded data is stored on a tangible medium on the tangible gift card.

System and method for generation of customized cards having a gift value associated therewith

This invention is directed to a system and method for storing font image data, which is already rendered, in a history-based order on the server side. This avoids the server side processing time to render the font every time a request is received. This allows users to use many server side fonts that users may not have on their client workstations. In the method, the user uses a web browser to choose a font type, size, and style from a list of available fonts installed on the server. The system then determines if the selected font exists in the font repository. If the font exists, the system retrieves the font images from the font repository. If the font does not exist, the system creates the font images and stores the font images to the font repository.

System and method for rendering fonts for tabbed paper stock on a network

The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.

Pyrrolidones with anti-HIV activity

An architecture for universal data communication between a network client and a web server. A web server receives a character string from the network client for storing. The web server encodes and then stores the string. Any character that is not a 7 bit ASCII character is encoded by encapsulating it with an escape code, the escape code comprised of an illegal character. Upon a request to retrieve the encoded string, the web server decodes and converts to UTF8 the encoded character string. When a client or browser requests the folder or document containing the encoded string, the string is properly displayed in the client's or browser's native language.

Method of encoding and decoding for multi-language applications

A system and method for accounting for document processing operations. Notification data is received from a networked document processing device, which indicates the presence on the network of the document processing device. Accounting data is then communicated to the networked document processing device in response to the notification data. The accounting data facilitates the administration of costs associated with the usage of the networked document processing device. Cost data is then received from the networked document processing device representing the accumulated costs associated with the usage of the document processing device. The cost data is accumulated according to the received accounting data by the networked document processing device.

System and method for document processing operation accounting

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San Diego, CA, United States of America

Truc Ngoc Nguyen