Evalve, Inc.

Advanced Cardiovascular Systems, Inc.

Gore Enterprise Holdings, Inc.

Other

W. L. Gore & Associates, Inc.

Abbott Vascular, Inc.

Abbott Cardiovascular Systems, Inc.

Cardio-renal Solutions, Inc.

Prograft Medical, Inc.

Eric A. Goldfarb

Alfred H. Raschdorf

Brian B. Martin

Ferolyn T. Powell

Sylvia Wen-chin Fan

Kent D. Dell

Troy L Thornton

Brian Benjamin Martin

Eric A Goldfarb

Ferolyn T Powell

Alfred H Raschdorf

Kent D Dell

Lilip Lau

Jaime Eduardo Sarabia

Yen C Liao

Sylvia Wen-Chin Fan

Jan Komtebedde

Sharon S Lam

Gerald Ray Martin

Scott N Stonebrook

Sylvia Erickson

Amy R Raatikka

Motasim Mahmoud Sirhan

Randy S Chan

Eric Williams

Lawrence D Wasicek

Patrick K Campbell

Alfred H Raschdorf, Jr

Steven Tyler

Jovito L Fernando, Sr

John P Madden

William Kolosi

Kristin Ellis

Jayanth Chakravarthy

Pedro Lucatero

John P Maddan

Ketan P Muni

Suresh Subraya Pai

Kamal Ramzipoor

Isidro Matias Gandionco

Robert C Laduca

Theodore W Ketai

Arundhati Kabe

Donald L Alden

Sylvia Wen-Chin Erickson

Chris Norcross Bender

Aaron M Weiss

Celso Jacinto Bagaoisan

Ramsin Gharibadeh

Susan M Feltovich

Brian B Martin

August R Yambao

Sandra Saenz

Steven A Tyler

Steve Tyler

Eric W Leopold

Joseph C Trautman

Thomas G Breton

Ted Ketai

Murli Srinivasan

Sylvia Wenchin Fan

Sharon Lam

Estela H Hilario

Sylvester B Lucatero

Francisco J Valencia

Pedro B Lucatero

Jr Alfred H Raschdorf

Roger A Goodgion

Chris Bender

Devices, systems and methods are provided for stabilizing and grasping tissues such as valve leaflets, assessing the grasp of these tissues, approximating and fixating the tissues, and assessing the fixation of the tissues to treat cardiac valve regurgitation, particularly mitral valve regurgitation.

Methods and devices for tissue grasping and assessment

A blood flow control device having a catheter adapted to be advanced into a blood vessel to a blood flow control site within the blood vessel; an expandable anchor supported by the catheter, the expandable anchor being adapted to expand to engage a wall of the blood vessel, the expandable anchor having a blood impermeable wall defining an adjustable blood flow path extending through the expandable anchor from a proximal opening to a distal opening, the catheter being disposed outside of the adjustable blood flow path; a flow control element supported by the catheter, the flow control element being adapted to change a dimension of the adjustable blood flow path to change a rate of blood flow through the blood flow path; and a blood flow control actuator disposed at a proximal section of the catheter and adapted to actuate the flow control element.

Device and method for variable blood flow occlusion

A delivery system for an interventional device includes an elongate catheter body, a catheter shaft extending within the elongate catheter body and configured to releasably attach to the interventional device, and at least one flexible element attached to a distal portion of the catheter shaft. The at least one flexible element has an expanded configuration in which the at least one flexible element extends beyond an outer circumference of the elongate catheter body and a collapsed configuration in which the at least one flexible element collapses within an inner circumference of the elongate catheter body. The at least one flexible element is configured to act as a tactile stop when pulled proximally against the elongate catheter body and/or to fold over the interventional device to act as a retraction aid.

Delivery system for mitral valve leaflet apposition device

Methods and apparatuses for pumping blood within a blood vessel are described. The methods and apparatuses can be used for renal decongestion by pumping blood through the kidney(s), thereby increasing a pressure gradient across the kidney(s). The apparatuses can include one or more inflatable elements that can be repeatedly inflated and deflated to cause a pumping action within the blood vessel. In some embodiments, the one or more inflatable elements are positioned within one or more stents.

Device for renal decongestion

Disclosed are methods, systems, and devices for the endovascular repair of cardiac valves, particularly the atrioventricular valves which inhibit back flow of blood from a heart ventricle during contraction. The procedures described herein can be performed with interventional tools, guides and supporting catheters and other equipment introduced to the heart chambers from the patient's arterial or venous vasculature remote from the heart. The interventional tools and other equipment may be introduced percutaneously or may be introduced via a surgical cut down, and then advanced from the remote access site through the vasculature until they reach the heart.

Methods, systems and devices for cardiac valve repair

System for fixation of leaflets of a heart valve including an implantable fixation device including a first distal element and a second distal element, a first proximal element moveable relative to the first distal element between a first position and a second position, and a second proximal element moveable relative to the second distal element between a first position and a second position. The system further includes a delivery device including a catheter having a proximal end portion and a distal end portion, the implantable fixation device releasably coupled to the distal end portion of the catheter, the catheter defining at least one lumen extending between the proximal end portion and the distal end portion. The delivery device further includes a first proximal element line extending through the at least one lumen, the first proximal element line coupled to the first proximal element and actuatable to move the first proximal element between the first position and second position, and a second proximal element line extending through the at least one lumen, the second proximal element line coupled to the second proximal element and actuatable to move the second proximal element between the first position and second position. The first proximal element line and the second proximal element line are independently actuatable.

Fixation devices, systems and methods for engaging tissue

The present invention provides methods and devices for grasping, and optional repositioning and fixation of the valve leaflets to treat cardiac valve regurgitation, particularly mitral valve regurgitation. Such grasping will typically be atraumatic providing a number of benefits. For example, atraumatic grasping may allow repositioning of the devices relative to the leaflets and repositioning of the leaflets themselves without damage to the leaflets. However, in some cases it may be necessary or desired to include grasping which pierces or otherwise permanently affects the leaflets. In some of these cases, the grasping step includes fixation.

Methods and devices for capturing and fixing leaflets in valve repair

A catheter configured for intraluminal delivery to a location in the body of a patient, the catheter comprising a steerable assembly comprising a first segment connected to a second segment; the first segment comprises first and second cylindrical elements connected to each other by a first revolute joint in a first single plane; the second segment comprises third and fourth cylindrical elements connected to each other by a second revolute joint in a second single plane, wherein the first single plane and the second single plane are offset by an angle from each other.

Steerable assembly for surgical catheter

Disclosed are devices and methods for treating regurgitation through a valve in the heart. The devices can include an expandable, fluid-tight bladder configured to be deployed between valve leaflets of the heart valve. The bladder can include an upper portion that extends into the atrium of the heart; a lower portion that extends into the ventricle of the heart; and a middle portion positionable within the line of valve leaflet coaptation that provides a sealing surface for one or more of the leaflets.

Devices, systems, methods and kits are provided for endoscopically accessing a body cavity and providing a directed pathway toward a target tissue within the cavity. The directed pathway is provided by a multi-catheter guiding system which is positioned in a desired configuration, generally directed toward the target tissue. Interventional devices may then be passed through the guiding system to the target tissue. Depending on the location of the target tissue and the desired angle of approach, the guiding system may be required to maintain one or more curves in one or more planes to properly direct the interventional devices. The multi-catheter guiding system of the present invention comprises an outer guiding catheter and a coaxially positioned inner guiding catheter, each of which independently form curvatures so that together the curves properly direct the interventional device.

Multi-catheter steerable guiding system and methods of use

A stent-graft including a stent member having an inner surface and an outer surface, a generally tubular graft member and a coupling member that couples the stent member to the graft member. The coupling member, which is the preferred embodiment is in the form of a ribbon, covers only a portion of the inner or outer surface of the stent member and secures the stent member and graft member to one another. Alternatively, the coupling member can be described as interconnecting less than entirely the inner or outer surface of the graft member to the stent member. With this construction, regions of the stent member do not interfere with the coupling member. Shear stresses between the stent member and the coupling member and the risk of tearing the graft or coupling member or delamination therebetween may be reduced as compared to a fully enveloped stent member. This construction also provides improved flexibility and kink resistance.

Kink resistant stent-graft

Growing community of inventors

San Francisco, CA, United States of America

Troy L Thornton