Celator Pharmaceuticals, Inc.

Troy Harasym

Lawrence D Mayer

Andrew S Janoff

Marcel B Bally

Paul Tardi

Murray Webb

Clifford Shew

Sharon Johnstone

Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.

Compositions for delivery of drug combinations

Compositions which comprise an anthracycline agent, and a cytidine analog are encapsulated in liposomal carriers. The preferred anthracycline agent is selected from the group of daunorubicin, doxorubicin, and idarubicin, while the preferred cytidine analog is selected from the group of cytarabine, gemcitabine, or 5-azacytidine. The combination of the anthracycline agent and cytidine analog encapsulated in said liposomal carriers are useful in achieving a drug retention and a sustained drug release for each therapeutic agent.

Liposomal formulations of anthracycline agents and cytidine analogs

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Vancouver, Canada

Troy Harasym