Suprapolix B.v.

Technische Universiteit Eindhoven

Xeltis Ag

Xeltis B.v.

Symo-chem B.v.

Tristan Mes

Anton Willem Bosman

Henricus Marie Janssen

Martijn Antonius Johannes Cox

Franciscus Petrus Thomas Baaijens

Patricia Yvonne Wilhelmina Dankers

Tom Lavrijsen

Anandkumar Nandakumar

Carolina Victoria Catharina Bouten

Serge Hendrikus Mathijs Söntjens

Joris Wilhelmus Peeters

Michel Henri Chrétien Joseph Van Houtem

Serge Hendrikus Mathijs SÖNTJENS

The present invention relates to supramolecular biomedical polymers comprising quadruple hydrogen bonding units and to a process for preparing such a supramolecular biomedical polymer and porous biomedical implants thereof. The supramolecular biomedical polymers are particularly suitable for the production of porous biomedical implants that need high strength, elasticity, durability, and slow biodegradation, e.g. medical implants for living tissue regeneration within a mammal, such as the treatment of cardio-vascular diseases, medical prolapses, and hernias.

Supramolecular biomedical polymers

The disclosure lies in the field of regenerative medicine and relates to an implant having a matrix material, and a method for manufacturing an implant having matrix material. The disclosure further relates to a crimped implant.

Implant

The present invention relates to a supramolecular biodegradable polymer comprising a quadruple hydrogen bonding unit (abbreviated herein as '4H-unit'), a biodegradable backbone and hard blocks and a process for preparing such a supramolecular biodegradable polymer. The supramolecular polymer is specifically suitable for biodegradable articles such as biomedical implants that need high strength and/or elasticity, e.g. medical implants in the cardio-vascular field.

Supramolecular biodegradable polymer

The present invention relates to a thermoplastic elastomer according to the formula [AB], wherein A represents a soft block and B represents a hard block. The present invention further relates to a process for the preparation of the thermoplastic elastomer. The thermoplastic material is in particular suited for biomaterial applications, for example for implants and tissue engineering applications and for purposes including scaffolding material applications, e.g. for tissue engineering purposes.

Strictly segmented thermoplastic elastomers as biodegradable biomaterials

This disclosure relates to new injectable hydrogel materials that consist of water gellants comprising linear hydrophilic polymers that comprise hydrogen bonding units in the backbone combined with cross-linkable end groups, resulting in dynamic yet firm hydrogel materials that are easily processable, are highly elastic, show adhesive properties and are self-healing and are especially suitable for biomedical applications.

Durable hydrogen bonded hydrogels

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Eindhoven, Netherlands

Tristan Mes