Chemocentryx, Inc.

Trevor T Charvat

Sreenivas Punna

Solomon Ungashe

Andrew M K Pennell

Jay Patrick Powers

Yibin Zeng

Cheng Hu

Anita Melikian

Manmohan Reddy Leleti

Christopher W Lange

Yandong Li

William L Thomas

Aaron Robert Novack

Edward J Sullivan

Jeff Jin

Venkat Reddy Mali

Ju Yang

Junfa Fan

Wei Yu Chen

Antoni Krasinski

Daniel J Dairaghi

Zheng Wei

Jimmie L Moore

John Jessen Wright

Arindrajit Basak

Derek Hansen

Penglie Zhang

Jeffrey P McMahon

Andrew Mk Pennell

Qiang Wang

Xuefei Tan

Hiufung Chu

Timothy J Sullivan

William D Thomas

Aaron Novack

Jeffrey P McMAHON

Jeffrey P MacMahon

Jeffrey P Mcmahon

Jimmie Moore

Daniel Dairaghi

Jay Powers

Andrew MK Pennell

Arindrajit Badak

Aniline compounds are provided which bind to CCR(4) and are useful for the treatment of diseases such as allergic diseases, autoimmune diseases, graft rejection and cancer.

Substituted anilines as CCR(4) antagonists

Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.

Heteroaryl sulfonamides and CCR2/CCR9

Compounds are provided that act as potent antagonists of the CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.

N-(2-(hetaryl)aryl)arylsulfonamides and N-(2-(hetaryl)hetaryl)arylsulfonamides

N-(2-(hetaryl)aryl)arylsulfonamides and n-(2-(hetaryl)hetaryl) arylsulfonamides

Pyrrolidinone carboxamide compounds are provided that are useful for inhibiting the binding of ligands to the ChemR23 receptor.

Pyrrolidinone carboxamide derivatives

Compounds are provided that act as potent antagonists of the CCR2 or CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2 and CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, CCR9-mediated diseases, as controls in assays for the identification of CCR2 antagonists and as controls in assays for the identification of CCR9 antagonists.

Triazolyl phenyl benzenesulfonamides

Triazolyl pyridyl benzenesulfonamides

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San Jose, CA, United States of America

Trevor T Charvat