S.d. Sight Diagnostics Ltd.

Trevor Ruggiero

Joseph Joel Pollak

Yochay Shlomo Eshel

Sharon Pecker

Sarah Levy Schreier

Amir Zait

Sarah Levy

Amitai Franklin

Aidan John Carroll

Apparatus and methods are described for use with a microscopy unit that comprises an objective lens and a microscope camera. A cantilever includes an objective lens housing. A motor moves the cantilever along a direction of the optical axis of the objective lens. The cantilever is configured, during the movement of the cantilever, to support the objective lens within the objective lens housing such that an optical axis of the objective lens is aligned with the camera, without the objective lens being directly connected to the camera. Other applications are also described.

Microscopy unit

Apparatus and methods are described including placing a sample into a sample carrier that comprises a plurality of regions having upper and lower surfaces, having respective heights that are different from each other, and being configured such that cells form a monolayer, the monolayer within respective regions of the sample carrier having respective, different densities from each other, due to the respective regions of the sample carrier having respective heights that are different from each other. Microscopic images are acquired of each of the plurality of regions. Measurements are performed upon cell types that have a relatively high density upon microscopic images of a region of the sample chamber having a relatively low height, and measurements are performed upon cell types that have a relatively low density upon microscopic images of a region of the sample chamber having a relatively great height. Other applications are also described.

Sample carrier for optical measurements

Apparatus and methods are described for determining a property of a biological sample. A sample carrier () includes one or more sample chambers () that define at least a first region () and a second region (), the height of the one or more sample chambers varying between the first and second regions in a predefined manner. A computer processor () receives data relating to a first optical measurement that is performed upon a portion of the sample that is disposed within the first region, receives data relating to a second optical measurement that is performed upon a portion of the sample that is disposed within the second region, and determines the property of the sample by using a relationship between the first optical measurement, the second optical measurement, and the predefined variation in height between the regions. Other applications are also described.

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Somerville, MA, United States of America

Trevor Ruggiero