Morpho Detection, Inc.

General Electric Company

Ge Homeland Protection, Inc.

Tracy Lynn Paxon

Frank John Mondello

Michael Craig Burrell

Christopher Montalbano

Gregory Anthony Montalbano

Aaron Klein

William Scott Sutherland

Radislav Alexandrovich Potyrailo

William Guy Morris

Cheryl Margaret Surman

Yuan-Hsiang Lee

Katharine Dovidenko

A method for increasing a spectroscopic signal in a biological assay is provided. The method includes forming a suspension of magnetically attractable particles. The method also includes introducing a first magnetic field at a first location to draw the magnetically attractable particles towards the first location and form a first agglomeration. The method also includes removing the first magnetic field. The method further includes introducing a second magnetic field at a second location to draw the first agglomeration towards the second location and form a second agglomeration. The method further includes focusing an excitation source on the second agglomeration formed at the second location.

System and method for increasing spectroscopic signal

A sensor is provided. The sensor comprises at least one sensing device comprising a first electrode and a second electrode, and a gap defined as a distance between one or more facing inner surfaces of the first and second electrodes, wherein the gap distance at least in part determines a threshold of one or more sensed parameters, and an antenna in operative association with the sensing device.

Sensors having gap based sensing devices and methods of making and using the same

A portable substance identification system and method are configured to identify at least one detection target faster and with greater accuracy than is possible using prior substance identification systems and/or prior substance identification techniques. An embodiment of the portable substance identification system includes a portable substance identification device containing a Raman spectrometer, and a collection stem that includes a dry collector. One or more reservoirs for a liquid medium and/or a reagent can be formed in a cartridge that is configured to couple with a portable substance identification device. The cartridge has a chamber in which the reagent, liquid medium, and a detection target picked up by the dry collector are mixed. A magnet, positioned at a slant angle, can be used to form at least one pellet of aggregated magnetic particles within a pellet forming area of the chamber. The pellet is formed to maximize its surface area.

System and method for improved biodetection

Portable substance identification system and method are configured to identify at least one detection target faster and with greater accuracy than is possible using prior substance identification systems and/or prior substance identification techniques. An embodiment of the portable substance identification system includes a portable substance identification device containing a Raman spectrometer, and a collection stem that includes a collector. One or more reservoirs for a liquid medium and/or at least one reagent can be formed in the collection stem. The cartridge can include a chamber in which the reagents, liquid medium, and at least one detection target picked up by the collector are mixed. A magnet, positioned at a slant angle, can be used to form at least one pellet of aggregated magnetic particles within a pellet forming area of the chamber. The pellet is formed to maximize its surface area.

Methods for amplifying the Raman signal of primary SERS nanoparticles are provided. One method generally includes binding secondary SERS particles to the primary SERS nanoparticles after binding of the primary SERS nanoparticles. In another method, secondary SERS nanoparticles are brought in close proximity to the primary SERS nanoparticles, wherein the secondary nanoparticles are free of a reporter molecule or have a reporter molecule different from that of the primary SERS nanoparticles.

Growing community of inventors

Waterford, NY, United States of America

Tracy Lynn Paxon