Sun Pharmaceutical Industries (australia) Pty Ltd

University of York

Glaxosmithkline Australia Pty Limited

Sun Pharmaceutical Industries Australia Limited

Tracy Carol Walker

Ian Alexander Graham

Thilo Hans Winzer

Tony Robert Larson

Thilo Winzer

Ian Graham

Fergus Meade

This disclosure relates to the isolation and sequencing of nucleic acid molecules that encode cytochrome P450 polypeptides from acultivar; uses in the production of noscapine and identification of poppy cultivars that include genes that comprise said nucleic acid molecules.

Plant cytochrome P450

Papaver somniferum cytochrome P450

This disclosure relates to the isolation of a nucleic acid molecule[s] that encode a novel cytochrome P450 and an oxidoreductase from a] cultivar, transgenic cells transformed with said nucleic acid molecule and sequence variants thereof; and including methods for the production of intermediates in the production of morphinans.

Cytochrome P450 fusion protein

The disclosure relates to a nucleic acid molecule isolated from acultivar that produces the opiate alkaloid noscapine which comprises 10 genes involved in the biosynthesis of opiate alkaloids.

Biosynthesis of opiate alkaloids

This disclosure relates to the isolation and sequencing of nucleic acid molecules that encode methyltransferase polypeptides from acultivar; and uses in the production of noscapine and identification of poppy cultivars that include the genes that include these nucleic acid molecules.

Methyltransferase nucleic acids and polypeptides

Growing community of inventors

Latrobe, Australia

Tracy Carol Walker