Cerus Corporation

University of California

Pfizer Corporation

Tovo David

Naheed Mufti

Anna Erickson

Betsy Donnelly

Shaun R Coughlin

Isaac J Rondon

Yun Cheol Kim

Lauren K Ely

Huilan Gao

Thomas Mikita

Provided are methods for preparing pathogen-inactivated platelet compositions, as well as processing sets and compositions related thereto.

Kits and methods for preparing pathogen-inactivated platelet compositions

In one aspect, antibodies, or antigen-binding fragments thereof, that specifically bind to activated Factor XI (FXIa) are provided. Also provided are methods of obtaining such antibodies and nucleic acids encoding the same. In another aspect, compositions and therapeutic prevention of thrombotic diseases, disorders or conditions are provided. In another aspect, anti-idiotype antibodies that bind anti-FXIa antibodies of the disclosure, as well as compositions comprising the anti-idiotype antibodies, methods of obtaining the antibodies and nucleic acids encoding the same, are also provided.

Antibodies to coagulation factor XIa and uses thereof

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San Francisco, CA, United States of America

Tovo David