Fujisawa Pharmaceutical Company, Ltd.

Toshiyasu Honbo

Takehisa Hata

Fumio Shimojo

Sotoo Asakura

Yoshio Ueda

Yoshiharu Tsuji

Akihiro Ishino

Kazutake Kado

Yasuto Koyama

Youhei Kiyota

Sachiyo Tanimoto

Hachiro Seno

Yasuo Shimazaki

Michihisa Nishiyama

Hiromitsu Yoshida

This invention relates to an aqueous liquid composition for external use which contains a tricyclo compound of the chemical formula (I) presented here-under or a pharmaceutically acceptable salt thereof. More particularly, the invention relates to an aqueous liquid composition for external use characterized in that it contains said tricyclo compound and a water-soluble solubilizer. The composition of the invention is used in medical treatment.

Aqueous liquid composition for external use

Macrolide compounds such as the FR-900506 and its related compounds are provided for the prevention or treatment of idiopathic thrombocytopenic purpura and Basedow's disease. Composition containing such compounds is also disclosed.

Medicament for treating idiopathic thrombocytopenic purpura

A hair revitalizing agent including a compound represented by the formula shown below or a pharmaceutically acceptable salt thereof: ##STR1## (wherein R.sup.1 to R.sup.10, R.sup.14 to R.sup.23, X, Y, and n are the same as defined in the present specification).

Hair revitalizing agent

This invention relates to a solid dispersion composition comprising FR-900506 substance and water-soluble hydroxypropyl methylcellulose which is capable of dispersing the FR-900506 substance, the FR-900506 substance and hydroxypropyl methylcellulose being in the ratio of 1:0:1 to 1:20 by weight.

Solid dispersion composition of FR-900506 substance

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Kobe, Japan

Toshiyasu Honbo