Chugai Seiyaku Kabushiki Kaisha

Nippon Television Network Corp.

Other

Mitsubishi Denki Kabushiki Kaisha

Toshiya Ito

Hiroshi Sakamoto

Takashi Emura

Yoshiyuki Ono

Yoshio Sugimori

Nobuhiro Oikawa

Hatsuo Kawada

Nobuya Ishii

Kenji Morikami

Noriyuki Furuichi

Kazutomo Kinoshita

Yasuharu Kato

MinJeong Park

WooSang Hong

Kohsuke Asoh

Yves C Faroudja

Atsushi Matsuo

Yoshihide Kimata

Mikimasa Tanada

Koji Takano

Kazuya Izuta

Yoshio Endo

Takeo Iida

Minoru Tamiya

Aya Chiyoda

The present inventors found cyclic peptide compounds that interact with Ras, and non-natural amino acids useful for the production of the cyclic peptide compounds. The inventors also found that the cyclic peptide compounds inhibit the binding between Ras and SOS. In addition, the inventors found specific non-natural amino acids contained in the cyclic peptide compounds and methods for production thereof.

Cyclic peptide compound having Kras inhibitory action

A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: 

Tetracyclic compound

A computer system analysis device (100) has an alternative system (7b) for monitoring a computer system (7a) to be analyzed. The operation flow is switched from the system (7a) to the alternative system (7b) when a system failure of the system (7a) happens. A data searching section (10) fetches data value stored in a crash dump file (8b), a device file (8c), and the like as data collection files by using address data obtained from a kernel load module file (8a) corresponding to data items of a system failure requested by an input/output section (9) through which an operator requests to the device (100) to display data items and values thereof stored in the data collection files. The input/output section (9) receives the data items and values thereof from the data searching section (10) and displays them per page. The systems (7a, 7b) are made up of different processor systems, respectively.

Computer system analysis device

A cooperative adaptive low noise television system provides that, prior to transmission, the composite video is separated into chroma and luminance components. The luminance signal is adaptively pre-emphasized, with the amount of pre-emphasis being determined by the luminance transitions level, so that small transitions have more pre-emphasis than large ones. In the receiver, a received luminence signal is submitted to adaptive deemphasis in order to precisely cancel the adaptive pre-emphasis provided prior to transmission, thus reducing transmission noise while restituting a luminance signal free of pre-shoot, over-shoot or resolution losses.

Adaptive operation type low noise television system

A television system, in which a picture is transmitted from an oblong screen to a television screen having an aspect ratio of 3:4, which is different from that of the oblong screen, and wherein no-picture portions are developed within upper and lower sections of the television screen, signals are transmitted into such upper and lower no-picture portions of the television screen in accordance with detected non-moving and moving picture portions of the oblong screen so as to improve the resolution of the picture image displayed upon the television screen.

Television system for transmitting auxiliary image signals in the black

Growing community of inventors

Tokyo, Japan

Toshiya Ito