Shionogi Company Limited

Nisshin Kasei Co., Ltd.

Daido Chemical Corporation

Other

Eli Lilly and Company

Toshiro Fujii

Yusuke Suzuki

Noboru Hoshi

Yoshihiro Furuya

Shunji Uramatsu

Toshio Shimamoto

Makoto Noami

Hiroshi Tanaka

Toyohiko Takeda

Peter L Oren

Nagayoshi Myo

Teruo Sakamoto

Neil R Anderson

Satoshi Sakuma

Toshihiro Ogura

Kinzaburo Noda

Yoshitaka Tomoda

Hisayoshi Kato

Hitoshi Kadota

Ikuo Tanai

The present invention relates to a novel resin composition useful as a coating agent or a binder for medicines, drugs for animals, agricultural chemicals, fertilizers, foods or the like, which contains a polyvinyl alcohol copolymer as a main component. More particularly, the present invention relates to a resin composition, characterized in that the composition is obtained by copolymerizing a polyvinyl alcohol having an average polymerization degree of 1300 or less, and at least one polymerizable vinyl monomer in a weight ratio of 6:4 to 9:1.

Coating composition

The present invention relates to a process for producing a spherical particle comprising an aggregate of particles containing at least 95% of a water-soluble single substance having a viscosity of 10 mPa.s or less as determined in the form of a saturated aqueous solution, the process comprising: preparing moist spherical particles of the single substance by charging, as cores, crystalline particles or granulated particles of the single substance on a rotary disc in a processing vessel of a centrifugal tumbling granulating apparatus, wherein the granulated particles are prepared by granulating a powder of the single substance, and dispersing over the cores a powder of the single substance and simultaneously spraying on the cores a liquid such as water or the like while supplying slit air to provide a fluidized condition; and then fixation treating the moist spherical particles by drying them while spraying an aqueous solution of the single substance or the like on the spherical particles in a fluidized bed apparatus; to the spherical particle produced by the process; and to a pharmaceutical preparation and a food containing the spherical particle.

Spherical single-substance particles, medicines and foodstuffs containing the particles, and method of production thereof

A sustained-release preparation which can release a highly water-soluble medicinally active ingredient over a long time and a process for the production thereof are provided. The preparation has a sustained-releasing layer formed by heating and melting a layer composed of both an aqueous ethylcellulose latex containing a plasticizer and a wax to miscibilize them.

Sustained-release preparation utilizing thermal change and process for the production thereof

A superior enteric formulation of the antidepressant drug, duloxetine, is in the form of enteric pellets of which the enteric layer comprises hydroxypropylmethylcellulose acetate succinate.

Duloxetine enteric pellets

Sustained-release formulations which can release a water-soluble active ingredient or ingredients at the zero-order over a long period of time, comprising:

Sustained-release formulation and production thereof

Growing community of inventors

Amagasaki, Japan

Toshiro Fujii