Sumitomo Metal Industries, Inc.

Shimizu Construction Co., Ltd.

Japan Corn Starch Co., Ltd

Toshio Uno

Hideo Shimizu

Kiyoshi Ikura

Masahiro Kato

Toshiyuki Niwa

Hiroshige Murase

Toshihiko Hirama

Fumio Ohtake

Yoshitaka Yabe

Masao Umezaki

Tomomi Kanemitsu

Takehiko Terada

Shinji Mase

A method for producing starch granules suitable as an excipient for an orally disintegrating tablet. Fluidized bed granulation is performed by spraying a starch paste in small amounts while a &#x3b2;-starch is being fluidized using an air-fluidized bed. Subsequently, fluidized bed drying is performed at a temperature equal to or higher than the gelatinization temperature of the &#x3b2;-starch. This yields starch granules having a high degree of gelatinization in comparison with the amount of &#x3b1;-starch adhered to the &#x3b2;-starch by the spraying of the starch paste. These starch granules alone impart satisfactory oral disintegratability and breaking strength to the tablet. Accordingly, when used as an excipient during tableting of orally disintegrating tablets, other auxiliary excipients such as saccharides or crystalline cellulose need not be added.

Method for producing starch granules, and orally disinitegrating tablet

The present invention provides an earthquake resistant multi-story building which is characterized by having an energy concentration story. The energy concentration story has an elasto-plastic force-displacement relationship regarding horizontal force and displacement. The force-displacement relationship is characterized in that: (a) stiffness in elastic range (F.sub.y /d.sub.y) is generally equal to an optimal stiffness of the same story according to an elastic design concept; (b) the yield strength F.sub.y is generally less than 80% of an optimum yield strength; (c) stiffness in plastic range is positive and generally less than about a half of the stiffness in the elastic range; and (d) ultimate displacement is generally at least twice as large as the yield displacement. The energy concentration story is capable of entering into the plastic range while other stories are in the elastic range, and absorbing vibration energy by plastic deformations thereof so as to decrease deformations of other stories when a large external force is exerted to the building.

Earthquake resistant multi-story building

Growing community of inventors

Tokyo, Japan

Toshio Uno