Kyorin Pharmaceutical Co., Ltd.

Kyorin Pharameuticals Co., Ltd.

Toshio Maeda

Masahiro Nomura

Koji Murakami

Katsuya Awano

Masaki Tsunoda

Susumu Kinoshita

Hiroya Satoh

Mitsutomo Miyashita

Fukutaro Taga

Fumio Kawahara

The present invention provides novel N-benzyldioxothiazolidylbenzamide derivatives that improve the insulin resistance and have potent hypoglycemic and lipid-lowering effects and processes for preparing the same, and relates to N-benzyldioxothiazolidylbenzamide derivatives characterized by being represented by a general formula (1) ##STR1## [wherein R.sup.1 and R.sup.2 denote identically or differently hydrogen atoms, lower alkyl groups with carbon atoms of 1 to 4, lower alkoxy groups with carbon atoms of 1 to 3, lower haloalkyl groups with carbon atoms of 1 to 3, lower haloalkoxy groups with carbon atoms of 1 to 3, halogen atoms, hydroxyl groups, nitro groups, amino groups which may be substituted with lower alkyl group(s) with carbon atoms of 1 to 3 or hetero rings, or R.sup.1 and R.sup.2 link to form a methylenedioxy group, R.sup.3 denotes a lower alkoxy group with carbon atoms of 1 to 3, hydroxyl group or halogen atom, and dotted line indicates double bond or single bond in combination with solid line], and processes for preparing the same.

N-benzyldioxothiazolidylbenzamide derivatives and process for producing

N-benzyldioxothiazolidylbenzamide derivatives and processes for

N-substituted dioxothiazolidylbenzamide derivatives and process for

N,N'-disubstituted amide derivatives

Growing community of inventors

Nogi-machi, Japan

Toshio Maeda