Mitsui Chemicals, Inc.

Toshio Kitashima

Hiroyuki Katsuta

Kenji Kodaka

Teruyuki Nagata

Kei Yoshida

Hideaki Oikawa

Hidetoshi Hayashi

Kanji Tomiya

Yutaka Chiba

Shingo Matsuo

Kouki Fukumura

Katsutoshi Kinoshita

Hiroshi Sonoda

Daisuke Ura

Hideki Umetani

Junko Naruse

Takeshi Kakimoto

Tsuyoshi Yasutake

Kenichi Satoh

Ken'ichi Goto

Takashi Shimaoka

Hisato Kamekawa

Kenichi Sato

Tomotaka Miyashita

Disclosed is a method for commercially producing 2-alkenyl-3-aminothiophene derivatives, which are useful as intermediates for agricultural chemicals, at low cost. Specifically disclosed is a method for introducing alkenyl groups into the 2-position of 3-aminothiophene derivatives by reacting 3-aminothiophene derivatives represented by the general formula (2) below or salts thereof with a ketone represented by the general formula (1) below without using a protecting group. Also specifically disclosed are 2-alkenyl-3-aminothiophene derivatives (3a) to (3d) which are useful as intermediates for agricultural chemicals, 

2-alkenyl-3-aminothiophene derivative and process for producing thereof

Disclosed is an improved process for producing nitroguanidine derivatives represented by the formula (3), which has an insecticidal activity, or a salt thereof, wherein the substituents are defined herein, in which nitroisourea derivatives represented by the following general formula (1) or a salt thereof wherein the substituents are defined herein, and compounds represented by the following general formula (2) or a salt thereof, wherein the substituents are defined herein, are reacted in the presence of a base in an aqueous solution wherein an inorganic salt is dissolved at not less than 50% of its saturated solubility.

Process for producing nitroguanidine derivatives

A method for reducing a sulfur-containing compound by hydrogenation using a noble metal catalyst which method is exemplified by an industrial method for producing a 2-alkyl-3-aminothiophene derivative with high economical efficiency by hydrogenating a 2-alkenyl-3-aminothiophene derivative using the noble metal catalyst. 2-Alkyl-3-aminothiophene derivatives are useful compounds in the fields of medicine and agriculture, and in particular, useful in bactericides for agriculture or gardening, or intermediates of the bactericides. The hydrogenation reaction temperature is controlled at 150&#xb0; C. to 300&#xb0; C. and the method allows the used noble metal catalyst to be recovered and reused.

Method for producing 2-alkyl-3-aminothiophene derivative

Fluorination agent and preparation and use of same

A 5-aminopyrazole-4-carboxylate derivative represented by the formula (1) is prepared by reacting a compound represented by the formula (2) with a hydrazine compound represented by the formula (3) or hydrate, hydrochloride, hydrobromide or sulfate of the same according to the reaction formula (C):

5-aminopyrazole-4-carboxylate derivative and process for preparing the same

3-Formyltetrahydrofuran is prepared by reacting 2,5-dihydrofuran with hydrogen and carbon monoxide in the presence of a group VIII metal compound and tris(2-t-butyl-5-methylphenyl) phosphite.

Method for production of 3-formyl-tetrahydrofuran

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Omuta, Japan

Toshio Kitashima