Konica Minolta, Inc.

Konica Minolta Opto, Inc.

Wako Pure Chemical Industries, Inc.

Konica Minolta Advanced Layers, Inc.

Toshinori Takimura

Hiroshi Hirayama

Soh Ohzawa

Naoki Shimizu

Junichi Jono

Takehiko Goshima

Takashi Washizu

Yoshiyuki Masuda

Shoichi Tao

Probe with a light-receiving optical fiber having an entrance face on the tip orthogonal to first optical axis; a light-emitting optical fiber having an exit face on the tip that is orthogonal to a second optical axis; and a lens with a positive refractive power that projects light exiting from the exit face onto the measurement site of a living tissue and focuses light radiated from the measurement site of the living tissue onto the entrance face. Lens has convex surface facing the entrance face and exit face, a flat surface formed on the side opposite the convex surface, and a third optical axis. Distance from center of convex surface to first optical axis of optical fiber is shorter than distance from center to second optical axis of optical fiber.

Probe

A probe which is inserted into a lumen of inside of a body, irradiates an observation object part of a physiological tissue with excitation light, and detects fluorescence resulting from the excitation light, wherein the probe including: a plus lens arranged facing toward a tip side of the probe; and a plurality of optical fibers receiving the fluorescence at tip surfaces through the plus lens, wherein the tip surface are directed toward the plus lens and arranged in positions offset from an optical axis of the plus lens, wherein positions of the tip surface of at least optical fibers of which an amount of offset from the optical axis of the plus lens differ mutually among plurality of optical fibers are shifted mutually along the optical axis of the plus lens.

A microchip having a substrate, a cover member joined to one surface of the substrate, and a flow path formed on at least one of joined surfaces of the substrate and the cover member, wherein the microchip includes: a well which is an first opening for communicating into the flow path with a surface opposite to the joined surface of the substrate and is arranged on the substrate; and a chimney which is a member arranged so as to project from the surface opposite to the joined surface of the substrate and has an second opening which communicating into the well, wherein a liquid rise prevention section is formed in the chimney to prevent the liquid from rising to a top portion of the chimney.

Microchip

Optical probe having, independently, an irradiation light guide path for irradiation light and a received light guide path for acquiring radiated light. A first optical fiber configures the irradiation light guide path, and a second optical fiber configures the received light guide path. A condensing lens receives on one surface irradiation light from the first optical fiber and emits same on the other surface, and receives radiated light radiated from the other surface and concentrates same on the side of the first and second optical fibers. The central axis of the exit end of the first optical fiber is deviated relative to the optical axis of the condensing lens, moving reflected light at the condensing lens surface away from, and moving radiated light concentrated by the condensing lens closer to, the center of the light-receiving end of the second optical fiber.

A microchipin which a resinous film can be inhibited from sagging into a channel. The microchipcomprises: a resinous substratehaving a channel groove formed therein; and a resinous film bonded to a surface of the substrate on which the channel groove has been formed. A micro-channelincluding channelsA and channelsB is formed by the channel groove and the resinous film. The total length of the channelsB, which is parallel to the X direction for the resinous substrate, is larger than the total length of the channelsA, which is parallel to the Y direction for the resinous substrate. The resinous substratehas been bonded to the resinous film so that the sides parallel to the channelsB are parallel to the TD direction of the resinous film and that the sides parallel to the channelsA are parallel to the MD direction of the resinous film.

Growing community of inventors

Hachioji, Japan

Toshinori Takimura