Sankyo Company, Limited

Toshinori Ohmine

Ichiro Kawashima

Hidehiko Furukawa

Tokio Tani

Jun Ohsumi

Yo Takiguchi

Takao Okazaki

Mamoru Arai

Taichi Manome

Yo Takiguichi

Human pancreatic elastase can now be obtained from a genetically engineered source.

Human pancreatic elastase

Human pancreatic elastase I can be obtained by genetic engineering.

Human pancreatic elastase I

A novel plasmid, named pSAN 181, has a molecular weight of 5.+-.0.2 megadaltons and single cleavage sites for each of the restriction endonucleases BamHI, PstI, XhoI and BglII, the positions of said sites being 0, about 0.85, about 1.15 and about 3.95 megadaltons from the cleavage site of BamHI. The plasmid is extracted from mycelia of microorganisms of the species Streptomyces fulvoviridis, especially the strain Streptomyces fulvoviridis FERM P-6279, and is useful as a vector for genetic engineering.

Plasmid pSAN 181

Growing community of inventors

Tokyo, Japan

Toshinori Ohmine