Asahi Kasei Medical Co., Ltd.

Toshinori Koizumi

Naoki Morita

Teruhiko Oishi

Hiroshi Tajima

Keitaro Matsuyama

Makoto Ozeki

Takayuki Yano

Takahiro Ichi

Yasuko Sato

Ryo Komura

A blood purification device includes a porous molded body containing an inorganic ion-adsorbing material and is characterized by the following: the concentrations of Mg, Al, Ti, V, Cr, Mn, Fe, Ni, Cu, Zn, Ga, Rb, Sr, Y, Zr, Mo, Ru, Ag, Cd, Sn, Cs, La, Pr, Sm, Gd, Tb, Ta, Au, Tl, Co, In, and Bi are each 0.1 ppb or less and the concentrations of Ba, Nd, Pb, And Ce are each 1 ppb or less in a physiological saline solution for injection both three months and six months after said physiological saline solution for injection is sealed in the blood purification device; and the number of fine particles having a size of 10 μm or more is 25 or less and the number of fine particles having a size of 25 μm or more is 3 or less in 1 mL of the physiological saline solution for injection.

Blood purification device and method for producing same

Provided is a blood purification device including a porous molded body that has a high phosphorus adsorption capacity and that can be used safely. A blood purification device includes a porous molded body containing an inorganic ion-adsorbing material and is characterized by the following: said blood purification device satisfies the relationship B=&#x2212;0.02 A+2.175&#xb1;0.185 (74&#x2264;A&#x2264;94) when the moisture content of the porous molded body is denoted by A and the bulk density is denoted by B; and the number of fine particles having a size of 10 &#x3bc;m or more is 25 or less and the number of fine particles having a size of 25 &#x3bc;m or more is 3 or less in 1 mL of a physiological saline solution for injection both three months and six months after said physiological saline solution for injection is sealed in the blood purification device.

The present invention provides a separation membrane for blood processing, comprising a polysulfone polymer, a hydrophilic polymer and a polymer having a hydroxy group in a side chain and having a solubility of 0.5 g or less in water (100 g) at 20&#xb0; C., in which the content of the polymer falls within a specific range, and a blood processing apparatus having the membrane installed therein.

Separation membrane for blood processing and blood processing apparatus having the membrane installed therein

To provide an efficient sterilization method for inexpensively sterilizing a medical article having a complex shape such as a body fluid treatment device of a generally-called dry or semi-dry type by so applying an electron beam that the overall absorbed dose distribution is small and to provide its application package form. [MEANS FOR SOLVING PROBLEMS] A method for sterilizing tubular body fluid treatment devices of a dry or semi-dry type contained in an electron beam-transmitting case with an electron beam. The method is characterized in that a stack structure which includes a gap layer having an average density of 0.010 to 0.180 g/cmand two body fluid treatment device layers having an average density of 0.050 to 0.200 g/cmand sandwiching the gap layer is contained in the electron beam-transmitting case, and the case is irradiated with the electron beam.

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Tokyo, Japan

Toshinori Koizumi