Chugai Seiyaku Kabushiki Kaisha

Toshinari Taira

Takeshi Nakamura

Kenta Wada

Katsuya Otomo

In manufacturing an aspherical seamless capsule comprises, firstly, a seamless capsule Chaving a filler encapsulated with a shell membrane is provided, then it is dried in a dryeruntil a predetermined percentage content of solvent in the shell membrane reaches a predetermined value. Subsequently, the seamless capsule is heated by a heaterso that the shell material may get to a semi-sol state. Then, the heated seamless capsule is formed into an aspherical shape using a forming machine such as a compression molding machine. Because the spherical seamless capsule has a shell membrane which is dried to get semi-sol so that it may have a reduced elasticity and a shortened stress relaxation time, the capsule can be formed in a short time and suppressed from restoring to the original spherical shape. The semi-sol shell membrane has almost no change in properties, and so allows easiness in temperature control for treatment. The aspherical capsule after being formed does not or rarely need drying, resulting in wrinkle resistance and little variation in shape brought on the surface of the shell membrane.

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Tokyo, Japan

Toshinari Taira