The University of Tokyo

Shimadzu Corporation

Perseus Proteomics Inc.

Fujifilm Ri Pharma Co., Ltd.

Toshimitsu Momose

Daisuke Saito

Hiroyuki Aburatani

Takao Hamakubo

Hiroko Iwanari

Hirotaka Itoh

Miwako Takahashi

Keisuke Ogaki

Tomohiko Sato

Tsutomu Soma

Yoshitaka Kumakura

Toshiko Sakihama

In order to provide a tomographic image analyzing apparatus which is simple and which obtains stable results, the tomographic image analyzing apparatus according to this invention includes an image standardizing unit which transforms PET images, in advance of tomographic image analysis, so that the contour of the brain of an subject appearing in the PET images become the contour of a brain represented by standard data. By carrying out such transforming operation before the analysis, there is no need to acquire MRI images like before, to be able to ease the burden on the subject. And according to this invention, the time of analysis is shortened. Further, according to this invention, an analysis of time variations of radioactive drug distribution is conducted with respect to a corresponding site on standardized PET images which corresponds to the ROI on the standard data. This can make analysis results stable.

Brain tomographic dynamic image analyzing apparatus

It is an object of the present invention to provide a novel antibody capable of specifically recognizing ROBO1 that is expressed in a cell membrane, a hybridoma that produces the above antibody, a method for producing the above antibody, and a tumor diagnostic agent used in PET comprising the above antibody. The present invention provides a monoclonal antibody capable of specifically recognizing ROBO1 existing on the surface of a cell, which is obtained by immunizing an animal to be immunized with a ROBO1-displaying budded baculovirus recovered from the culture supernatant of host cells infected with a recombinant baculovirus comprising the full-length cDNA of ROBO1 as an antigen.

Tumor diagnostic agent used in PET comprising anti-ROBO1 antibody

Growing community of inventors

Tokyo, Japan

Toshimitsu Momose