Otsuka Pharmaceutical Company, Limited

Educational Foundation Jichi Medical University

Toshiki Sudo

Shigeto Yoshida

The invention provides a pharmaceutical composition comprising at least one polypeptide of the following (a) to (d): (a) a polypeptide comprising the amino acid sequence of SEQ ID NO:1; (b) a polypeptide comprising an amino acid sequence comprising one or more amino acid deletions, insertions, substitutions or additions in the amino acid sequence of the above (a) and having a platelet aggregation inhibitory activity and/or a platelet adhesion inhibitory activity;(c) a polypeptide comprising the amino acid sequence of SEQ ID NO:3; and(d) a polypeptide comprising an amino acid sequence comprising one or more amino acid deletions, insertions, substitutions or additions in the amino acid sequence of the above (c) and having a platelet aggregation inhibitory activity and/or a platelet adhesion inhibitory activity,as an active component.

Platelet aggregation inhibitor composition

The invention provides a pharmaceutical composition comprising at least one polypeptide of the following (a) to (d):

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Sokushima, Japan

Toshiki Sudo